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Rat C-X-C motif chemokine 3(CXCL3) ELISA kit

  • 中文名稱:
    大鼠C-X-C趨化因子3(CXCL3)酶聯(lián)免疫試劑盒
  • 貨號(hào):
    CSB-EL006249RA
  • 規(guī)格:
    96T/48T
  • 價(jià)格:
    ¥3600/¥2500
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品描述:
    大鼠C-X-C趨化因子3(CXCL3)酶聯(lián)免疫試劑盒(CSB-EL006249RA)為雙抗夾心法ELISA試劑盒,定量檢測(cè)血清、血漿、組織勻漿樣本中的CXCL3含量。CXCL3,也稱為CXC趨化因子配體3,是一種中性粒細(xì)胞的趨化因子,屬于CXC趨化因子亞家族。CXCL3在多種免疫反應(yīng)中發(fā)揮作用,包括傷口愈合、癌癥轉(zhuǎn)移和血管生成。它在腫瘤發(fā)生中發(fā)揮重要作用,尤其是在頭頸部鱗狀細(xì)胞癌(HNSCC)中,其表達(dá)水平與預(yù)后相關(guān),可能通過(guò)影響腫瘤細(xì)胞的分化、侵襲和遷移來(lái)促進(jìn)腫瘤生長(zhǎng)。試劑盒檢測(cè)范圍為15.6 pg/ml- 1000 pg/ml,靈敏度為3.9 pg/ml。適用于體外炎癥模型構(gòu)建、免疫機(jī)制探索、藥物干預(yù)效果評(píng)價(jià)等科研場(chǎng)景;為研究CXCL3在病理生理過(guò)程中的作用機(jī)制提供可靠工具;支持96孔板規(guī)格批量檢測(cè),滿足實(shí)驗(yàn)室多樣本、高通量研究需求本品僅用于科研,不用于臨床診斷,產(chǎn)品具體參數(shù)及操作步驟詳見(jiàn)產(chǎn)品說(shuō)明書(shū)。
  • 別名:
    Cxcl3 ELISA kit; Cinc2C-X-C motif chemokine 3 ELISA kit; Cytokine-induced neutrophil chemoattractant 2 ELISA kit; CINC-2 ELISA kit; Macrophage inflammatory protein 2-alpha/beta ELISA kit; MIP2-alpha/beta ELISA kit
  • 縮寫:
  • Uniprot No.:
  • 種屬:
    Rattus norvegicus (Rat)
  • 樣本類型:
    serum, plasma, tissue homogenates
  • 檢測(cè)范圍:
    15.6 pg/ml - 1000 pg/ml
  • 靈敏度:
    3.9 pg/ml
  • 反應(yīng)時(shí)間:
    1-5h
  • 樣本體積:
    50-100ul
  • 檢測(cè)波長(zhǎng):
    450 nm
  • 研究領(lǐng)域:
    Immunology
  • 測(cè)定原理:
    quantitative
  • 測(cè)定方法:
    Sandwich
  • 數(shù)據(jù)處理:
  • 貨期:
    3-5 working days

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Ligand for CXCR2. Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion.
  • 基因功能參考文獻(xiàn):
    1. this study shows elevated expression of CINC-2 at the site of inflammation as well as their significant reflection in the circulation, thereby suggesting their frontline role in carrageenan-induced acute inflammation PMID: 27967265
    2. CINC-2beta is regulated differently from most other chemokines and that its expression is related to the state of alveolar type II cell differentiation. PMID: 16055671
  • 亞細(xì)胞定位:
    Secreted.
  • 蛋白家族:
    Intercrine alpha (chemokine CxC) family
  • 數(shù)據(jù)庫(kù)鏈接: