Rat Cathepsin B(CTSB) ELISA kit
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中文名稱:大鼠組織蛋白酶B(CTSB)酶聯(lián)免疫試劑盒
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貨號:CSB-EL006185RA
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規(guī)格:96T/48T
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價格:¥3600/¥2500
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其他:
產(chǎn)品詳情
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產(chǎn)品描述:大鼠組織蛋白酶B(CTSB)酶聯(lián)免疫試劑盒(CSB-EL006185RA)為雙抗夾心法ELISA試劑盒,定量檢測血清、血漿、組織勻漿、細(xì)胞裂解物樣本中的CTSB含量。CTSB即組織蛋白酶B,是溶酶體半胱氨酸蛋白酶家族的成員。它在細(xì)胞內(nèi)蛋白質(zhì)代謝等方面發(fā)揮重要作用。研究發(fā)現(xiàn)其異常表達(dá)與腫瘤、神經(jīng)退行性疾病等多種疾病相關(guān),機(jī)制涉及促進(jìn)腫瘤細(xì)胞侵襲轉(zhuǎn)移、參與神經(jīng)細(xì)胞凋亡等。試劑盒檢測范圍為18.75 ng/mL-1200 ng/mL,適用于體外實驗研究,可支持基礎(chǔ)科研中CTSB在細(xì)胞模型、動物疾病模型或藥物干預(yù)實驗中的動態(tài)監(jiān)測,例如溶酶體功能分析、組織損傷修復(fù)機(jī)制探索或相關(guān)信號通路研究,為深入解析CTSB的生物學(xué)功能及病理學(xué)意義提供可靠工具。本品僅用于科研,不用于臨床診斷,產(chǎn)品具體參數(shù)及操作步驟詳見產(chǎn)品說明書。
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別名:Ctsb ELISA Kit; Cathepsin B ELISA Kit; EC 3.4.22.1 ELISA Kit; Cathepsin B1 ELISA Kit; RSG-2) [Cleaved into: Cathepsin B light chain; Cathepsin B heavy chain] ELISA Kit
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縮寫:
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Uniprot No.:
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種屬:Rattus norvegicus (Rat)
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樣本類型:serum, plasma, tissue homogenates, cell lysates
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檢測范圍:18.75 ng/mL-1200 ng/mL
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靈敏度:4.67 ng/mL
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反應(yīng)時間:1-5h
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樣本體積:50-100ul
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檢測波長:450 nm
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研究領(lǐng)域:Signal Transduction
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測定原理:quantitative
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測定方法:Sandwich
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數(shù)據(jù)處理:
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貨期:3-5 working days
引用文獻(xiàn)
- Graphene oxide induces p62/SQSTM-dependent apoptosis through the impairment of autophagic flux and lysosomal dysfunction in PC12 cells Feng X.et al,Acta Biomaterialia,2018
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能:Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Cleaves matrix extracellular phosphoglycoprotein MEPE. Involved in the solubilization of cross-linked TG/thyroglobulin in the thyroid follicle lumen. Has also been implicated in tumor invasion and metastasis.
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亞細(xì)胞定位:Lysosome. Melanosome. Secreted, extracellular space. Apical cell membrane; Peripheral membrane protein; Extracellular side.
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蛋白家族:Peptidase C1 family
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組織特異性:Expressed in the epithelial cells of the prostate and mammary gland.
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數(shù)據(jù)庫鏈接:
STRING: 10116.ENSRNOP00000014178
UniGene: Rn.100909
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