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Rat L-Selectin ELISA kit

  • 中文名稱:
    大鼠L選擇素(L-Selectin/CD62L)酶聯(lián)免疫試劑盒
  • 貨號:
    CSB-E07431r
  • 規(guī)格:
    96T/48T
  • 價格:
    ¥3900/¥2500
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品描述:
    大鼠L選擇素(L-Selectin/CD62L)酶聯(lián)免疫試劑盒(CSB-E07431r)為雙抗夾心法ELISA試劑盒,定量檢測血清、血漿、組織勻漿樣本中的SELL含量。SELL 即選擇素 L,是一種細胞表面黏附分子。其背景在于參與白細胞與血管內(nèi)皮細胞的初始黏附。研究機制上,它通過與配體結(jié)合,促使白細胞沿血管壁滾動,在炎癥反應、免疫細胞遷移等過程中發(fā)揮重要作用,是相關(guān)疾病研究的潛在靶點。試劑盒檢測范圍為78.125 pg/mL-5000 pg/mL,靈敏度為64 pg/mL??蒲腥藛T可借助本試劑盒開展免疫調(diào)控機制、炎癥性疾病模型評價或藥物干預研究,例如在實驗性自身免疫疾病、感染模型或組織損傷修復等研究中定量分析L選擇素動態(tài)變化,為探索白細胞遷移相關(guān)分子機制提供高靈敏度工具。本品僅用于科研,不用于臨床診斷,產(chǎn)品具體參數(shù)及操作步驟詳見產(chǎn)品說明書。
  • 別名:
    Sell; Lnhr; Ly-22; L-selectin; CD62 antigen-like family member L; Leukocyte adhesion molecule 1; LAM-1; Leukocyte-endothelial cell adhesion molecule 1; LECAM1; Lymph node homing receptor; Lymphocyte antigen 22; Lymphocyte surface MEL-14 antigen; CD antigen CD62L
  • 縮寫:
  • Uniprot No.:
  • 種屬:
    Rattus norvegicus (Rat)
  • 樣本類型:
    serum, plasma, tissue homogenates
  • 檢測范圍:
    78.125 pg/mL-5000 pg/mL
  • 靈敏度:
    64 pg/mL
  • 反應時間:
    1-5h
  • 樣本體積:
    50-100ul
  • 檢測波長:
    450 nm
  • 研究領(lǐng)域:
    Stem Cells
  • 測定原理:
    quantitative
  • 測定方法:
    Sandwich
  • 數(shù)據(jù)處理:
  • 貨期:
    3-5 working days

產(chǎn)品評價

靶點詳情

  • 功能:
    Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia.
  • 亞細胞定位:
    Cell membrane; Single-pass type I membrane protein.
  • 蛋白家族:
    Selectin/LECAM family
  • 組織特異性:
    Expressed in peripheral blood mononuclear cells (PBMC), spleen and thymus.
  • 數(shù)據(jù)庫鏈接: