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  4. Rat Regenerating islet-derived protein 3-gamma(REG3G) ELISA kit

Rat Regenerating islet-derived protein 3-gamma(REG3G) ELISA kit

  • 中文名稱(chēng)：
    大鼠再生胰島衍生蛋白3γ(REG3G）酶聯(lián)免疫試劑盒
  • 貨號(hào)：
    CSB-EL019549RA
  • 規(guī)格：
    96T/48T
  • 價(jià)格：
    ￥3600/￥2500
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品描述：
    大鼠再生胰島衍生蛋白3γ(REG3G）酶聯(lián)免疫試劑盒（CSB-EL019549RA）為雙抗夾心法ELISA試劑盒，定量檢測(cè)血清、血漿、組織勻漿樣本中的REG3G含量。REG3G 是一個(gè)重要靶點(diǎn)。其它在多種生理過(guò)程及疾病發(fā)生發(fā)展中可能扮演關(guān)鍵角色。研究機(jī)制上，科學(xué)家致力于探究其表達(dá)調(diào)控機(jī)制、與其他分子的相互作用等，以了解它如何參與細(xì)胞活動(dòng)和疾病進(jìn)程，為疾病治療提供新方向。試劑盒檢測(cè)范圍為1.56 ng/mL-100 ng/mL，為科研人員研究胰腺炎、糖尿病模型或腸道感染等實(shí)驗(yàn)場(chǎng)景中REG3G的動(dòng)態(tài)表達(dá)提供了精準(zhǔn)工具，可用于探索其在組織再生、先天免疫應(yīng)答中的分子機(jī)制及病理生理關(guān)聯(lián)性研究。本品僅用于科研，不用于臨床診斷，產(chǎn)品具體參數(shù)及操作步驟詳見(jiàn)產(chǎn)品說(shuō)明書(shū)。
  • 別名：
    Reg3g ELISA Kit; Pap3 ELISA Kit; Regenerating islet-derived protein 3-gamma ELISA Kit; REG-3-gamma ELISA Kit; Pancreatitis-associated protein 3 ELISA Kit; Regenerating islet-derived protein III-gamma ELISA Kit; Reg III-gamma) [Cleaved into: Regenerating islet-derived protein 3-gamma 16.5 kDa form; Regenerating islet-derived protein 3-gamma 15 kDa form] ELISA Kit
  • 縮寫(xiě)：
    REG3G
  • Uniprot No.：
  • 種屬：
    Rattus norvegicus (Rat)
  • 樣本類(lèi)型：
    serum, plasma, tissue homogenates
  • 檢測(cè)范圍：
    1.56 ng/mL-100 ng/mL
  • 靈敏度：
    0.39 ng/mL
  • 反應(yīng)時(shí)間：
    1-5h
  • 樣本體積：
    50-100ul
  • 檢測(cè)波長(zhǎng)：
    450 nm
  • 研究領(lǐng)域：
    Immunology
  • 測(cè)定原理：
    quantitative
  • 測(cè)定方法：
    Sandwich
  • 數(shù)據(jù)處理：
  • 貨期：
    3-5 working days

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Restricts bacterial colonization of the intestinal epithelial surface and consequently limits activation of adaptive immune responses by the microbiota. The uncleaved form has bacteriostatic activity, whereas the cleaved form has bactericidal activity against L.monocytogenes and methicillin-resistant S.aureus. Regulates keratinocyte proliferation and differentiation after skin injury.
  • 基因功能參考文獻(xiàn)：
    1. The Reg3G gene plays a major role in communication between injured axons and muscle and may play a significant role in skeletal muscle and peripheral nerve regeneration. PMID: 23588857
    2. released PAP-III might be cleaved and forms DeltaN-PAP-III fibers at the nerve injury sites. Consequently, these resulting fibers would provide regenerating axons with a platform for extension. PMID: 23426365
    3. results demonstrate that PAP-III is a novel macrophage chemoattractant that is involved in peripheral nerve regeneration PMID: 16837594
    4. pancreatitis-associated protein-III is associated with bladder inflammation in cystits PMID: 18295254
  • 亞細(xì)胞定位：
    Secreted. Cytoplasm.
  • 組織特異性：
    Expressed in injured skeletal muscles and sciatic nerve (at protein level). Expressed in the pancreas. Expression increases during the acute phase of pancreatitis.
  • 數(shù)據(jù)庫(kù)鏈接：

    KEGG: rno:24620

    STRING: 10116.ENSRNOP00000008665

    UniGene: Rn.9729