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  4. Sheep Luteinizing Hormone (LH) ELISA Kit

Sheep Luteinizing Hormone (LH) ELISA Kit

  • 中文名稱：
    綿羊黃體生成素（LH）酶聯(lián)免疫試劑盒
  • 貨號(hào)：
    CSB-E14019Sh
  • 規(guī)格：
    96T/48T
  • 價(jià)格：
    ￥4200/￥3000
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品描述：
    綿羊黃體生成素（LH）酶聯(lián)免疫試劑盒（CSB-E14019Sh）為雙抗夾心法ELISA試劑盒，定量檢測(cè)血清、血漿、組織勻漿樣本中的LH含量。LH即促黃體生成素，是腺垂體分泌的促性腺激素。其在生殖生理中背景重要，參與調(diào)節(jié)卵巢和睪丸功能。研究機(jī)制方面，它作用于性腺細(xì)胞表面受體，促進(jìn)性激素合成與分泌，在女性排卵及黃體形成等過(guò)程、男性睪酮生成中發(fā)揮關(guān)鍵作用。該產(chǎn)品適用于綿羊繁殖周期監(jiān)測(cè)、卵巢功能評(píng)估、生殖疾病模型研究等科研場(chǎng)景，為畜牧繁殖管理、激素調(diào)控機(jī)制探索及生殖健康相關(guān)基礎(chǔ)研究提供可靠工具。本品僅用于科研，不用于臨床診斷，產(chǎn)品具體參數(shù)及操作步驟詳見(jiàn)產(chǎn)品說(shuō)明書。
  • 別名：
    LHBLutropin subunit beta ELISA Kit; Lutropin beta chain ELISA Kit; Interstitial cell-stimulating hormone ELISA Kit; Luteinizing hormone subunit beta ELISA Kit; LH-B ELISA Kit; LSH-B ELISA Kit; LSH-beta) [Cleaved into: LH beta-1; LH beta-2; LH beta-3] ELISA Kit
  • 縮寫：
    LH
  • Uniprot No.：
  • 種屬：
    Ovis aries (Sheep)
  • 樣本類型：
    serum, plasma, tissue homogenates
  • 檢測(cè)范圍：
  • 反應(yīng)時(shí)間：
    1-5h
  • 樣本體積：
    50-100ul
  • 檢測(cè)波長(zhǎng)：
    450 nm
  • 研究領(lǐng)域：
    Signal Transduction
  • 測(cè)定原理：
    quantitative
  • 測(cè)定方法：
    Sandwich
  • 精密度：

    Intra-assay Precision (Precision within an assay): CV%<15%

     

    Three samples of known concentration were tested twenty times on one plate to assess.

     

    Inter-assay Precision (Precision between assays): CV%<15%

     

    Three samples of known concentration were tested in twenty assays to assess.

     

     

     

  • 線性度：

     To assess the linearity of the assay, samples were spiked with high concentrations of Sheep Luteinizing Hormone(LH) in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.

  • 數(shù)據(jù)處理：
  • 貨期：
    3-5 working days

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. The LH alpha 3/LH beta 3 heterodimer was shown to have potent renotropic and weak gonadotropic activity.
  • 基因功能參考文獻(xiàn)：
    1. Data indicate that the neuropeptide RFamide-related peptide 3 (RFRP-3) has no effect onluteinizing hormone secretion. PMID: 26862995
    2. This study indicates that endogenous opiates play a crucial role in the mechanism inhibiting GnRH/LH axis activity in lactating sheep and that the ligands for mu opioid receptor may have the highest inhibitory effect. PMID: 23953813
    3. Data suggest dietary components (phytoestrogens here) down-regulate basal secretion/total production of follicle stimulating hormone (CGA+FSHB) yet up-regulate gonadotropin-releasing hormone agonist-induced LH (CGA+LHB) secretion in gonadotrophs. PMID: 24050980
    4. These results indicate that the reproductive system can respond acutely to infusion of metabolic fuels such as propionate, although a sustained recovery of pulsatile LH secretion requires more than an increase in this single metabolic substrate. PMID: 21668532
    5. In ewes, infusion with genistein decreased the level of LHbeta in the adenohypophysis. PMID: 15531133

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  • 亞細(xì)胞定位：
    Secreted.
  • 蛋白家族：
    Glycoprotein hormones subunit beta family
  • 數(shù)據(jù)庫(kù)鏈接：

    KEGG: oas:443395

    UniGene: Oar.442