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N Monoclonal Antibody

Rare Species
  • 中文名稱：
    N鼠單克隆抗體
  • 貨號(hào)：
    CSB-MA33255A0m
  • 規(guī)格：
    ￥1320
  • 圖片：
    • The Binding Activity of SARS-CoV-2-N Antibody with SARS-CoV-2-N Activity: Measured by its binding ability in a functional ELISA. Immobilized SARS-CoV-2-N (CSB-EP3325GMY) at 2 μg/ml can bind SARS-CoV-2-N Antibody, the EC50 is 13.93 to 25.98 ng/ml.
    • Western Blot
      Positive WB detected in: SARS-CoV-2 nucleocapsid recombinant protein from E. Coli (CSB-EP3325GMY) at 40ng, 20ng, 10ng
      All lanes N antibody at 1:1000
      Secondary
      Goat polyclonal to mouse IgG at 1/50000 dilution
      Predicted band size: 48 KDa
      Observed band size: 55 KDa
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品描述：
    N Monoclonal Antibody（CUSABIO貨號(hào)：CSB-MA33255A0m）是針對(duì)新冠病毒（SARS-CoV-2/2019-nCoV）核衣殼蛋白（N蛋白）研發(fā)的高特異性檢測(cè)工具，適用于病毒基礎(chǔ)研究與抗病毒藥物開發(fā)領(lǐng)域。作為冠狀病毒的核心結(jié)構(gòu)蛋白，N蛋白在病毒基因組RNA的包裝及宿主免疫逃逸中發(fā)揮關(guān)鍵作用，是研究病毒復(fù)制機(jī)制與宿主相互作用的重要靶點(diǎn)。本產(chǎn)品采用雜交瘤技術(shù)制備，具有嚴(yán)格的種屬特異性，可精準(zhǔn)識(shí)別新冠病毒N蛋白抗原表位，經(jīng)嚴(yán)格驗(yàn)證適用于酶聯(lián)免疫吸附測(cè)定（ELISA）與免疫組織化學(xué)（IHC）實(shí)驗(yàn)體系。在新冠病毒感染機(jī)制研究、疫苗研發(fā)效果評(píng)估及抗病毒藥物篩選等科研場(chǎng)景中，該抗體能夠有效實(shí)現(xiàn)病毒蛋白的定性及半定量檢測(cè)，為建立病毒蛋白檢測(cè)標(biāo)準(zhǔn)、解析感染后免疫應(yīng)答特征提供可靠工具。其優(yōu)異的熱穩(wěn)定性與批次間一致性可保障實(shí)驗(yàn)數(shù)據(jù)的可重復(fù)性，是新冠病毒基礎(chǔ)研究與轉(zhuǎn)化醫(yī)學(xué)領(lǐng)域的重要實(shí)驗(yàn)材料。
  • Uniprot No.：
  • 別名：
    N; Nucleoprotein; N; Nucleocapsid protein; NC; Protein N
  • 宿主：
    Mouse
  • 反應(yīng)種屬：
    Human Novel Coronavirus (SARS-CoV-2/ 2019-nCoV)
  • 免疫原：
    Recombinant Human Novel Coronavirus Nucleoprotein (N) (1-419aa) (CSB-EP3325GMY)
  • 免疫原種屬：
    Human Novel Coronavirus (SARS-CoV-2/ 2019-nCoV)
  • 標(biāo)記方式：
    Non-conjugated
  • 克隆類型：
    Monoclonal
  • 抗體亞型：
    IgG1
  • 純化方式：
    >95%, Protein G purified
  • 克隆號(hào)：
    9B2F3-1
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    WB, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1000-5000
    ELISA 1:1000-1:5000
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. May modulate transforming growth factor-beta signaling by binding host smad3.
  • 亞細(xì)胞定位：
    Virion. Host cytoplasm.
  • 蛋白家族：
    Betacoronavirus nucleocapsid protein family