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ACTA2/ACTG2 Monoclonal Antibody

  • 中文名稱(chēng)：
    ACTA2/ACTG2鼠單克隆抗體
  • 貨號(hào)：
    CSB-MA166134
  • 規(guī)格：
    ￥1320
  • 圖片：
    • IHC image of CSB-MA166134 diluted at 1:100 and staining in paraffin-embedded human heart tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-mouse IgG polymer labeled by HRP and visualized using 0.05% DAB.
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品描述：
    CUSABIO貨號(hào)：CSB-MA166134 ACTA2/ACTG2單克隆抗體是針對(duì)α-平滑肌肌動(dòng)蛋白（ACTA2）和γ-平滑肌肌動(dòng)蛋白（ACTG2）研發(fā)的高特異性科研試劑，適用于人源樣本的免疫學(xué)檢測(cè)。ACTA2作為血管平滑肌細(xì)胞標(biāo)志物，參與血管收縮及細(xì)胞骨架構(gòu)建，其異常表達(dá)與動(dòng)脈硬化、纖維化疾病相關(guān)；ACTG2則特異性表達(dá)于內(nèi)臟平滑肌，在胃腸道蠕動(dòng)及膀胱功能調(diào)控中起關(guān)鍵作用。本產(chǎn)品采用雜交瘤技術(shù)制備，經(jīng)ELISA和免疫組化（IHC）雙重驗(yàn)證，能精準(zhǔn)識(shí)別兩種異構(gòu)體的保守表位，適用于體外蛋白定量檢測(cè)及組織切片中平滑肌細(xì)胞的定位研究。在科研領(lǐng)域可應(yīng)用于血管生物學(xué)研究、消化道動(dòng)力機(jī)制探索、腫瘤微環(huán)境分析等方向，為心血管疾病模型構(gòu)建、纖維化病理機(jī)制解析提供可靠工具。該抗體具有批次穩(wěn)定性高、種屬交叉反應(yīng)低的特點(diǎn)，是研究平滑肌細(xì)胞分化、組織重塑及疾病相關(guān)信號(hào)通路的優(yōu)選試劑。關(guān)鍵詞：ACTA2單抗、ACTG2抗體、人源ELISA試劑、免疫組化抗體、平滑肌細(xì)胞標(biāo)記物、血管生物學(xué)研究。
  • Uniprot No.：
  • 宿主：
    Mouse
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Synthesized peptide derived from human Actin, smooth muscle (SMA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 克隆類(lèi)型：
    Monoclonal
  • 抗體亞型：
    IgG2a, Kappa
  • 純化方式：
    The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
  • 克隆號(hào)：
    27A8
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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