CUSABIO貨號(hào)：CSB-MA085459 CDK1單克隆抗體是針對(duì)細(xì)胞周期關(guān)鍵調(diào)控因子CDK1（Cyclin-dependent kinase 1）研發(fā)的高特異性科研試劑。CDK1作為細(xì)胞周期G2/M期轉(zhuǎn)換的核心激酶，通過與細(xì)胞周期蛋白B結(jié)合形成復(fù)合物驅(qū)動(dòng)有絲分裂進(jìn)程，其異常表達(dá)與腫瘤發(fā)生、神經(jīng)退行性疾病等病理過程密切相關(guān)。該抗體采用雜交瘤技術(shù)制備，經(jīng)ELISA、Western Blot和免疫細(xì)胞化學(xué)（ICC）嚴(yán)格驗(yàn)證，可精準(zhǔn)識(shí)別人類、犬類、大鼠及小鼠種屬的CDK1蛋白，適用于細(xì)胞周期調(diào)控機(jī)制研究、癌癥發(fā)生發(fā)展相關(guān)信號(hào)通路解析、神經(jīng)退行性疾病模型構(gòu)建等基礎(chǔ)科研領(lǐng)域。在實(shí)驗(yàn)應(yīng)用中能有效檢測(cè)內(nèi)源性CDK1蛋白表達(dá)水平，為細(xì)胞增殖研究、藥物靶點(diǎn)篩選、分子互作分析等實(shí)驗(yàn)提供可靠工具，其優(yōu)異的種屬交叉反應(yīng)性尤其適合跨物種比較研究。本產(chǎn)品嚴(yán)格遵循科研級(jí)抗體質(zhì)量標(biāo)準(zhǔn)，為細(xì)胞周期相關(guān)研究提供高靈敏度和特異性的檢測(cè)解決方案。

cyclin-dependent kinase 1 p34 protein kinase cell cycle controller CDC2 cell division protein kinase 1 cell division control protein 2 homolog cell division cycle 2, G1 to S and G2 to M

Mouse

Human,Dog,Rat,Mouse

Recombinant fragment, corresponding to amino acids 8-298aa of Human CDC2.

Homo sapiens (Human)

Monoclonal

IgG2b

Antigen Affinity Purified

27H3

It differs from different batches. Please contact us to confirm it.

Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol

ELISA,WB,ICC

Application	Recommended Dilution
WB	1:500-1:5000
ICC	1:50-1:200

ELISA Protocol
Western Blotting (WB) Protocol

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

For Research Use Only. Not for use in diagnostic or therapeutic procedures.