FOXO1 Monoclonal Antibody
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中文名稱(chēng):FOXO1鼠單克隆抗體
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貨號(hào):CSB-MA075284
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規(guī)格:¥2621
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其他:
產(chǎn)品詳情
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產(chǎn)品描述:FOXO1單克隆抗體(CUSABIO貨號(hào):CSB-MA075284)是針對(duì)叉頭盒O1(Forkhead Box O1,F(xiàn)OXO1)轉(zhuǎn)錄因子研發(fā)的高特異性科研試劑。FOXO1作為胰島素信號(hào)通路的關(guān)鍵調(diào)控因子,在細(xì)胞代謝平衡、氧化應(yīng)激響應(yīng)及細(xì)胞周期調(diào)控中發(fā)揮重要作用,其異常表達(dá)與代謝性疾病、腫瘤發(fā)生等病理過(guò)程密切相關(guān)。本產(chǎn)品采用雜交瘤技術(shù)制備,經(jīng)嚴(yán)格驗(yàn)證可精準(zhǔn)識(shí)別人源與小鼠來(lái)源的FOXO1蛋白,適用于酶聯(lián)免疫吸附(ELISA)、蛋白質(zhì)免疫印跡(WB)及免疫細(xì)胞化學(xué)(ICC)等多種實(shí)驗(yàn)體系。在ELISA檢測(cè)中可定量分析FOXO1表達(dá)水平,WB實(shí)驗(yàn)?zāi)芮逦尸F(xiàn)約82kDa的目標(biāo)條帶,ICC技術(shù)則支持亞細(xì)胞定位研究。該抗體適用于探索FOXO1在糖脂代謝調(diào)控、衰老相關(guān)信號(hào)通路及疾病分子機(jī)制中的功能,為構(gòu)建基因敲除模型、驗(yàn)證蛋白互作網(wǎng)絡(luò)提供可靠工具,助力于糖尿病、癌癥等領(lǐng)域的分子機(jī)制研究。產(chǎn)品嚴(yán)格遵循科研用抗體標(biāo)準(zhǔn),確保實(shí)驗(yàn)數(shù)據(jù)的可重復(fù)性與準(zhǔn)確性,是生命科學(xué)基礎(chǔ)研究的理想選擇。
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別名:forkhead box protein O1 forkhead box protein O1A forkhead, Drosophila, homolog of, in rhabdomyosarcoma
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宿主:Mouse
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反應(yīng)種屬:Human,Mouse
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免疫原:Recombinant fragment, corresponding to amino acids 420-649aa of Human FOXO1(C-terminus).
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免疫原種屬:Homo sapiens (Human)
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克隆類(lèi)型:Monoclonal
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抗體亞型:IgG2a
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純化方式:Antigen Affinity Purified
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克隆號(hào):30B10
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濃度:It differs from different batches. Please contact us to confirm it.
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產(chǎn)品提供形式:Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
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應(yīng)用范圍:ELISA,WB,ICC
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推薦稀釋比:
Application Recommended Dilution WB 1:500-1:5000 ICC 1:50-1:200 -
Protocols:
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儲(chǔ)存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途:For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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