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  4. G4S linker Monoclonal Antibody

G4S linker Monoclonal Antibody

  • 中文名稱：
    G4S linker CAR檢測工具
  • 貨號：
    CSB-MA186062I1m
  • 規(guī)格：
    ￥3000
  • 圖片：
    • The Binding Activity of G4S linker with Anti-G4S linker antibody
      Activity: Measured by its binding ability in a functional ELISA. Immobilized Three recombinant proteins containing G4S linker at 2 μg/mL can bind Anti-G4S linker antibody. The EC50 is 5.223 to 18.40 ng/mL, 17.89 to 45.51 ng/mL and 2.705 to 8.752 ng/mL.
    • Untransfected HEK-293F cells (green line) and transfected scFv-based Anti-CD19 CAR containing a G4S linker stable cells (red line) were stained with anti-G4S linker antibody (2μg/1*106cells), washed and then followed by APC-conjugated anti-Mouse IgG Fc antibody and analyzed with flow cytometry.
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品描述：
    CUSABIO貨號：CSB-MA186062I1m人源G4S linker單克隆抗體是CAR-T細(xì)胞治療研究領(lǐng)域的高特異性檢測工具，專為識別嵌合抗原受體結(jié)構(gòu)中的G4S柔性連接子設(shè)計(jì)。該抗體采用雜交瘤技術(shù)制備，可特異性結(jié)合CAR分子中連接抗體重鏈（VH）與輕鏈（VL）的關(guān)鍵結(jié)構(gòu)域，適用于ELISA和流式細(xì)胞術(shù)（FC 1:50-1:200）兩種檢測平臺。作為通用型CAR陽性率檢測試劑，其核心價(jià)值在于支持CAR-X細(xì)胞療法（包括CAR-T、CAR-NK、CAR-M等）的研發(fā)質(zhì)控環(huán)節(jié)，幫助科研人員精準(zhǔn)評估工程化免疫細(xì)胞的CAR表達(dá)水平，為細(xì)胞制備工藝優(yōu)化、功能驗(yàn)證及體內(nèi)外藥效研究提供可靠數(shù)據(jù)支撐。該產(chǎn)品嚴(yán)格滿足科研級抗體標(biāo)準(zhǔn)，尤其適用于腫瘤免疫治療基礎(chǔ)研究、新型CAR結(jié)構(gòu)開發(fā)及細(xì)胞治療產(chǎn)品的臨床前研究體系驗(yàn)證。
  • 基因名：
    G4S linker
  • 別名：
    G4S, G4S linker
  • 宿主：
    Mouse
  • 反應(yīng)種屬：
    Homo sapiens (Human)
  • 免疫原：
    G4S-BSA
  • 標(biāo)記方式：
    Non-conjugated
  • 克隆類型：
    Monoclonal
  • 抗體亞型：
    IgG2b
  • 純化方式：
    >95%, Protein G purified
  • 克隆號：
    11A12E7
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, FC
  • 推薦稀釋比：
    Application Recommended Dilution
    FC 1:50-1:200
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價(jià)