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G4S linker Monoclonal Antibody

  • 中文名稱:
    G4S linker CAR檢測工具
  • 貨號:
    CSB-MA186062I3m
  • 規(guī)格:
    ¥3000
  • 圖片:
    • The Binding Activity of G4S linker with Anti-G4S linker antibody
      Activity: Measured by its binding ability in a functional ELISA. Immobilized Three recombinant proteins containing G4S linker at 2 μg/mL can bind Anti-G4S linker antibody. The EC50 is 4.229 to 7.004 ng/mL, 8.589 to 15.31 ng/mL and 3.323 to 4.195 ng/mL.
    • Untransfected HEK-293F cells (green line) and transfected scFv-based Anti-CD19 CAR containing a G4S linker stable cells (red line) were stained with anti-G4S linker antibody (2μg/1*106cells), washed and then followed by APC-conjugated anti-Mouse IgG Fc antibody and analyzed with flow cytometry.
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品描述:
    CUSABIO貨號:CSB-MA186062I3m G4S linker單克隆抗體是針對柔性連接肽結(jié)構(gòu)域研發(fā)的高特異性科研試劑,可精準(zhǔn)識別由甘氨酸-絲氨酸重復(fù)序列(GGGGS)構(gòu)成的重組蛋白連接區(qū)域。該抗體經(jīng)雜交瘤技術(shù)制備,具有出色批次穩(wěn)定性,適用于人源樣本的ELISA檢測與流式細(xì)胞分析。作為重組蛋白工程中廣泛應(yīng)用的分子"鉸鏈",G4S linker通過柔性的多肽鏈連接不同功能域,在抗體藥物開發(fā)、雙特異性蛋白構(gòu)建及融合蛋白設(shè)計中發(fā)揮關(guān)鍵作用。本產(chǎn)品經(jīng)嚴(yán)格驗證具備高親和力與低交叉反應(yīng)性,可有效檢測重組蛋白結(jié)構(gòu)完整性,為抗體工程改造、蛋白相互作用研究及生物大分子構(gòu)效關(guān)系分析提供可靠工具。實驗數(shù)據(jù)顯示其對不同表達(dá)系統(tǒng)制備的含G4S linker重組蛋白均表現(xiàn)出優(yōu)異檢測性能,是生命科學(xué)領(lǐng)域研究蛋白結(jié)構(gòu)功能、優(yōu)化生物制劑設(shè)計的重要檢測工具。該抗體適用于重組蛋白質(zhì)量評估、分子互作實驗驗證等應(yīng)用場景,為抗體藥物開發(fā)、基因工程蛋白研究等科研項目提供精準(zhǔn)檢測支持。
  • 基因名:
    G4S linker
  • 別名:
    G4S, G4S linker
  • 宿主:
    Mouse
  • 反應(yīng)種屬:
    Homo sapiens (Human)
  • 免疫原:
    G4S-BSA
  • 標(biāo)記方式:
    Non-conjugated
  • 克隆類型:
    Monoclonal
  • 抗體亞型:
    IgG2a
  • 純化方式:
    >95%, Protein G purified
  • 克隆號:
    14A10E7
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA, FC
  • 推薦稀釋比:
    Application Recommended Dilution
    FC 1:50-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價