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  4. KRT14/KRT16/KRT5/KRT6A/KRT8 Monoclonal Antibody

KRT14/KRT16/KRT5/KRT6A/KRT8 Monoclonal Antibody

  • 中文名稱：
    KRT14/KRT16/KRT5/KRT6A/KRT8鼠單克隆抗體
  • 貨號：
    CSB-MA789445
  • 規(guī)格：
    ￥1320
  • 圖片：
    • IHC image of CSB-MA789445 diluted at 1:100 and staining in paraffin-embedded human breast cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-mouse IgG polymer labeled by HRP and visualized using 0.05% DAB.
    • IHC image of CSB-MA789445 diluted at 1:100 and staining in paraffin-embedded human skin tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-mouse IgG polymer labeled by HRP and visualized using 0.05% DAB.
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品描述：
    CUSABIO貨號：CSB-MA789445單克隆抗體靶向KRT14、KRT16、KRT5、KRT6A及KRT8蛋白，該抗體組合適用于角蛋白網(wǎng)絡(luò)互作機(jī)制研究及上皮細(xì)胞標(biāo)記物檢測。作為細(xì)胞骨架關(guān)鍵組分，KRT5/KRT14異二聚體參與基底上皮細(xì)胞形態(tài)維持，KRT6A/KRT16復(fù)合物在皮膚損傷修復(fù)及應(yīng)激反應(yīng)中發(fā)揮調(diào)控作用，而KRT8異常表達(dá)與上皮間質(zhì)轉(zhuǎn)化及腫瘤轉(zhuǎn)移相關(guān)。本產(chǎn)品經(jīng)ELISA及免疫組化技術(shù)驗(yàn)證，對人源樣本具有特異性識別能力，適用于皮膚屏障功能研究、腫瘤微環(huán)境分析、上皮細(xì)胞分化追蹤等科研場景。抗體采用雜交瘤技術(shù)制備，具有高批次穩(wěn)定性與特異性結(jié)合優(yōu)勢，可為皮膚病理機(jī)制探索、腫瘤生物學(xué)特性研究及再生醫(yī)學(xué)領(lǐng)域提供可靠工具，滿足多靶點(diǎn)同步檢測需求，助力角蛋白家族在細(xì)胞動力學(xué)及疾病模型中的功能解析。
  • Uniprot No.：
  • 宿主：
    Mouse
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Synthesized peptide derived from human Cytokeratin Pan
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 克隆類型：
    Monoclonal
  • 抗體亞型：
    IgG2b, Kappa
  • 純化方式：
    The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
  • 克隆號：
    18E12
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價(jià)