CUSABIO貨號(hào)：CSB-MA913719 SMAD2單克隆抗體是針對(duì)人源SMAD2蛋白研發(fā)的高特異性科研試劑，采用雜交瘤技術(shù)生產(chǎn)，適用于ELISA、Western Blot及免疫細(xì)胞化學(xué)（ICC）等多種實(shí)驗(yàn)場(chǎng)景。SMAD2是TGF-β信號(hào)通路中關(guān)鍵信號(hào)轉(zhuǎn)導(dǎo)分子，參與調(diào)控細(xì)胞增殖、分化及腫瘤微環(huán)境等生物學(xué)過程，其異常表達(dá)與纖維化疾病、腫瘤轉(zhuǎn)移等病理機(jī)制密切相關(guān)。該抗體基于重組蛋白免疫策略開發(fā)，經(jīng)多平臺(tái)驗(yàn)證可特異性識(shí)別天然及變性狀態(tài)的人源SMAD2蛋白，在Western Blot中可清晰檢測(cè)約52kDa的目標(biāo)條帶，ICC實(shí)驗(yàn)顯示優(yōu)異的亞細(xì)胞定位性能，適用于研究SMAD2在細(xì)胞信號(hào)轉(zhuǎn)導(dǎo)、上皮間質(zhì)轉(zhuǎn)化（EMT）及疾病模型中的功能調(diào)控。作為專為科研設(shè)計(jì)的工具抗體，該產(chǎn)品能為TGF-β通路研究、腫瘤分子機(jī)制探索及藥物靶點(diǎn)驗(yàn)證等基礎(chǔ)研究提供可靠支持，配套多種緩沖體系可靈活適配不同實(shí)驗(yàn)方案需求。核心關(guān)鍵詞：SMAD2抗體、TGF-β信號(hào)通路、單克隆抗體、Western Blot試劑、細(xì)胞信號(hào)研究。

hMAD 2; hMAD-2; hSMAD2; JV18 1; JV18; JV18; JV18-1; JV181; MAD; MAD; MAD homolog 2; MAD Related Protein 2; Mad-related protein 2; MADH2; MADR2; MGC22139; MGC34440; Mothers Against Decapentaplegic Homolog 2; Mothers Against Decapentaplegic Homolog 2;

Mouse

Human

Purified recombinant Human SMAD2 protein fragments expressed in E.coli.

Homo sapiens (Human)

Monoclonal

IgG1

2D9

It differs from different batches. Please contact us to confirm it.

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

ELISA,WB,ICC

Application	Recommended Dilution
WB	1:500-1:5000
ICC	1:50-1:200

ELISA Protocol
Western Blotting (WB) Protocol

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

For Research Use Only. Not for use in diagnostic or therapeutic procedures.