SMAD5 Monoclonal Antibody
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中文名稱:SMAD5鼠單克隆抗體
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貨號:CSB-MA052999
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規(guī)格:¥2621
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其他:
產(chǎn)品詳情
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產(chǎn)品描述:SMAD5單克隆抗體(CUSABIO貨號:CSB-MA052999)是針對TGF-β信號通路關(guān)鍵調(diào)控因子SMAD5開發(fā)的科研專用試劑,該靶點通過介導骨形態(tài)發(fā)生蛋白(BMP)信號傳導參與細胞增殖、分化及胚胎發(fā)育調(diào)控。本產(chǎn)品采用高特異性雜交瘤技術(shù)制備,經(jīng)ELISA、Western Blot(WB)、免疫細胞化學(ICC)及流式細胞術(shù)(FC)多平臺驗證,可精準識別人類、豬、大鼠及小鼠等哺乳動物來源的SMAD5蛋白,適用于腫瘤微環(huán)境研究、干細胞定向分化實驗及骨骼發(fā)育相關(guān)機制探索。其優(yōu)異的種屬交叉反應性為跨物種比較研究提供便利,特別適合開展BMP/SMAD信號通路在癌癥轉(zhuǎn)移、組織再生修復中的功能解析,以及基因敲除模型驗證等實驗場景。該抗體在4℃長期儲存條件下保持穩(wěn)定活性,重復實驗結(jié)果一致性高,是探索TGF-β超家族信號網(wǎng)絡(luò)調(diào)控機制的高效工具。通過優(yōu)化抗原表位篩選工藝,有效降低非特異性結(jié)合干擾,助力研究人員在蛋白質(zhì)相互作用、亞細胞定位分析等前沿領(lǐng)域獲得可靠數(shù)據(jù)。
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別名:mothers against decapentaplegic homolog 5 SMA- and MAD-related protein 5 SMAD, mothers against DPP homolog 5 MAD, mothers against decapentaplegic homolog 5 mothers against decapentaplegic, drosophila, homolog of, 5
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宿主:Mouse
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反應種屬:Human,Pig,Rat,Mouse
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免疫原:Recombinant fragment, corresponding to amino acids 239aa-372aa of Human SMAD5 (C-terminus).
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免疫原種屬:Homo sapiens (Human)
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克隆類型:Monoclonal
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抗體亞型:IgG1
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純化方式:Antigen Affinity Purified
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克隆號:14E2
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濃度:It differs from different batches. Please contact us to confirm it.
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產(chǎn)品提供形式:Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
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應用范圍:ELISA,WB,ICC,FC
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推薦稀釋比:
Application Recommended Dilution WB 1:500-1:5000 ICC 1:50-1:200 -
Protocols:
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儲存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途:For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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