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A4GNT Antibody

  • 中文名稱：
    A4GNT兔多克隆抗體
  • 貨號：
    CSB-PA020263
  • 規(guī)格：
    ￥1090
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    A4GNT
  • 別名：
    4-N-acetylglucosaminyltransferase antibody; A4GCT_HUMAN antibody; A4GNT antibody; Alpha 1 4 N acetylglucosaminyltransferase antibody; Alpha-1 antibody; Alpha4GnT antibody; EC 2.4.1. antibody; MGC149493 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human α4Gn-T.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    WB, IHC, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:40000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能：
    Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. Necessary for the synthesis of type III mucin which is specifically produced in the stomach, duodenum, and pancreatic duct. May protect against inflammation-associated gastric adenocarcinomas.
  • 基因功能參考文獻(xiàn)：
    1. human alpha1,4-N-acetylglucosaminyltransferase (alpha4GnT) is responsible for O-glycan biosynthesis and has a role in preventing gastric cancer by inhibiting H. pylori infection and also suppressing tumor-promoting inflammation PMID: 22307328
    2. Up-regulation of alpha-1,4-N-acetylglucosaminyltransferase is associated with pancreatic cancer PMID: 16441422
  • 亞細(xì)胞定位：
    Golgi apparatus membrane; Single-pass type II membrane protein.
  • 蛋白家族：
    Glycosyltransferase 32 family
  • 組織特異性：
    Detected in stomach and pancreas.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 17968

    KEGG: hsa:51146

    STRING: 9606.ENSP00000236709

    UniGene: Hs.278960