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  4. ADAM29 Antibody

ADAM29 Antibody

  • 中文名稱：
    ADAM29兔多克隆抗體
  • 貨號：
    CSB-PA986639
  • 規(guī)格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using CSB-PA986639(ADAM29 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA986639(ADAM29 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    ADAM29
  • 別名：
    A disintegrin and metalloproteinase domain 29 antibody; ADA29_HUMAN antibody; ADAM 29 antibody; ADAM metallopeptidase domain 29 antibody; ADAM29 antibody; Cancer/testis antigen 73 antibody; CT73 antibody; Disintegrin and metalloproteinase domain-containing protein 29 antibody; Metallaproteinase disintegrin (ADAM29) antibody; svph1 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Synthetic peptide of Human ADAM29
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    May be involved in spermatogenesis and fertilization. Seems to be a non catalytic metalloprotease-like protein.
  • 基因功能參考文獻(xiàn)：
    1. Increased transcript expression of ADAM29 was observed in breast cancer tissues compared to normal ones. The expression of ADAM29 and its mutations in different domains significantly influenced proliferation, migration and invasion of breast cancer cells in vitro. PMID: 26977022
    2. PCMC expression of ADAM29, FLRT2, and SLC18A3 could be assessed as part of a routine screen to help identify individuals at risk of severe Obstructive sleep apnea in Asian populations PMID: 24732660
    3. mutated ADAM27 and ADAM7 genes could play a role in melanoma progression. PMID: 21618342
    4. quantification of LPL and ADAM29 gene expression is a strong prognostic indicator in CLL, providing better prognostic assessment than ZAP-70 in advanced stages of the disease PMID: 15802535
    5. Results support the use of LPL and ADAM29 gene expression associated to IGHV mutational status for predicting the clinical outcome of patients treated by oral fludarabine + cyclophosphamide and could be considered for treatment strategies. PMID: 19340428

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  • 相關(guān)疾?。?/div>
    Has been found to be frequently mutated in melanoma. ADAM7 mutations may play a role in melanoma progression and metastasis.
  • 亞細(xì)胞定位：
    Membrane; Single-pass type I membrane protein.
  • 組織特異性：
    Expressed specifically in testes.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 207

    OMIM: 604778

    KEGG: hsa:11086

    STRING: 9606.ENSP00000352177

    UniGene: Hs.126838