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ADSS Antibody

  • 中文名稱：
    ADSS兔多克隆抗體
  • 貨號：
    CSB-PA001398ESR1HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Western blot
      All lanes: Adenylosuccinate synthetase isozyme 2 antibody at 12μg/ml
      Lane 1: Mouse skeletal muscle tissue
      Lane 2: HepG2 whole cell lysate
      Lane 3: K562 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 50 kDa
      Observed band size: 50 kDa
    • Immunohistochemistry of paraffin-embedded human colon tissue using CSB-PA001398ESR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA001398ESR1HU at dilution of 1:100
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) ADSS Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    ADSS
  • 別名：
    ADSS2 antibody; ADSS antibody; Adenylosuccinate synthetase isozyme 2 antibody; AMPSase 2 antibody; AdSS 2 antibody; EC 6.3.4.4 antibody; Adenylosuccinate synthetase antibody; acidic isozyme antibody; Adenylosuccinate synthetase antibody; liver isozyme antibody; L-type adenylosuccinate synthetase antibody; IMP--aspartate ligase 2 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human, Mouse
  • 免疫原：
    Recombinant Human Adenylosuccinate synthetase isozyme 2 protein (1-280AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.
  • 基因功能參考文獻(xiàn)：
    1. Kinetic data reveal that human Ser(289) and B. subtilis Ser(262) and Ser(263) are essential for catalysis, while the ability of these Ser mutants to bind APBADP suggests that they do not contribute to substrate affinity PMID: 18469177
    2. These findings suggest that the combined effects of the polymorphisms in the ADSS and ATM genes may confer susceptibility to the development of schizophrenia in a Chinese population PMID: 19115993
  • 亞細(xì)胞定位：
    Cytoplasm. Mitochondrion. Note=Partially associated with particulate fractions.
  • 蛋白家族：
    Adenylosuccinate synthetase family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 292

    OMIM: 103060

    KEGG: hsa:159

    STRING: 9606.ENSP00000355493

    UniGene: Hs.498313