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  4. ANXA13 Antibody

ANXA13 Antibody

  • 中文名稱：
    ANXA13兔多克隆抗體
  • 貨號：
    CSB-PA151772
  • 規(guī)格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA151772(ANXA13 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using CSB-PA151772(ANXA13 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 8%SDS-PAGE, Lysate: 60 μg, Lane: Mouse small intestine tissue, Primary antibody: CSB-PA151772(ANXA13 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 minutes
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    ANXA13
  • 別名：
    Annexin A13 antibody; Annexin XIII antibody; Annexin; intestine-specific antibody; Annexin-13 antibody; ANX 13 antibody; ANX A13 antibody; ANX13 antibody; ANX13_HUMAN antibody; ANXA13 antibody; Intestine Specific Annexin antibody; Intestine-specific annexin antibody; ISA antibody; MGC150460 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse
  • 免疫原：
    Fusion protein of Human ANXA13
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
    IHC 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Binds to membranes enriched in phosphatidylserine or phosphatidylglycerol in a calcium-dependent manner. Half-maximal membrane binding requires about 60 uM calcium. Does not bind to membranes that lack phospholipids with an acidic headgroup.; Binds to membranes enriched in phosphatidylserine or phosphatidylglycerol in a calcium-dependent manner, but requires higher calcium levels for membrane binding than isoform A. Half-maximal membrane binding requires about 320 uM calcium.
  • 基因功能參考文獻：
    1. ANXA13 is associated with colorectal cancer cell invasion in vitro, and with lymph node metastasis and poor survival in colorectal cancer patients PMID: 28423508
    2. High ANXA13 expression is associated with Refractory Lupus Nephritis. PMID: 26110394
    3. Ectopic overexpression of Annexin A13 was likewise sufficient to sensitize malignant breast cancer cells to treatment with Rapamycin. PMID: 20701074
    4. The unique, conserved aspects of annexin A13 primary structure, gene organization, and genetic maps identify it as the probable common ancestor of all vertebrate annexins. PMID: 11961095
  • 亞細胞定位：
    Apical cell membrane. Cell membrane; Lipid-anchor. Cytoplasmic vesicle.
  • 蛋白家族：
    Annexin family
  • 組織特異性：
    Detected in epithelial cells in colon and jejunum (at protein level). Detected in epithelial cells in jejunum.
  • 數據庫鏈接：

    HGNC: 536

    OMIM: 602573

    KEGG: hsa:312

    STRING: 9606.ENSP00000262219

    UniGene: Hs.181107