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APOBEC3D Antibody

  • 中文名稱：
    APOBEC3D兔多克隆抗體
  • 貨號：
    CSB-PA846585LA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA846585LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA846585LA01HU at dilution of 1:100
    • Immunofluorescence staining of Hela cells with CSB-PA846585LA01HU at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) APOBEC3D Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    A3D antibody; ABC3D_HUMAN antibody; APOBEC3D antibody; APOBEC3DE antibody; APOBEC3E antibody; Apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3D antibody; Apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3E pseudogene antibody; ARP6 antibody; bK150C2.9 antibody; BK150C2.9 protein antibody; DNA dC >dU editing enzyme APOBEC 3D antibody; DNA dC->dU-editing enzyme APOBEC-3D antibody; hCG_41704 antibody; HCG41704; isoform CRA_b antibody; Probable DNA dC->dU-editing enzyme APOBEC-3D antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human DNA dC->dU-editing enzyme APOBEC-3D protein (250-371AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，APOBEC3D Antibody (CSB-PA846585LA01HU)，的標記方式是Non-conjugated。對于APOBEC3D Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產(chǎn)品名稱 應用
    HRP CSB-PA846585LB01HU APOBEC3D Antibody, HRP conjugated ELISA
    FITC CSB-PA846585LC01HU APOBEC3D Antibody, FITC conjugated
    Biotin CSB-PA846585LD01HU APOBEC3D Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. Exhibits antiviral activity against Vif-deficient HIV-1. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells. Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single- or double-stranded RNA. May inhibit the mobility of LTR and non-LTR retrotransposons.
  • 亞細胞定位：
    Cytoplasm. Cytoplasm, P-body.
  • 蛋白家族：
    Cytidine and deoxycytidylate deaminase family
  • 組織特異性：
    Expressed in lymphoid organs. Also detected in non-lymphoid tissues including lung.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 17354

    OMIM: 609900

    STRING: 9606.ENSP00000216099

    UniGene: Hs.629775