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ARF3 Antibody

  • 中文名稱：
    ARF3兔多克隆抗體
  • 貨號(hào)：
    CSB-PA001990ESR1HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Western blot
      All lanes: ARF3 antibody at 6μg/ml + Mouse brain tissue
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 21, 17 kDa
      Observed band size: 21 kDa
    • Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA001990ESR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA001990ESR1HU at dilution of 1:100
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) ARF3 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    ADP ribosylation factor 3 antibody; ADP-ribosylation factor 3 antibody; ARF3 antibody; ARF3_HUMAN antibody; small GTP binding protein antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human, Mouse
  • 免疫原：
    Recombinant Human ADP-ribosylation factor 3 protein (1-181AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:20-1:200
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.
  • 基因功能參考文獻(xiàn)：
    1. Upregulation of ARF3 is associated with ovarian cancer. PMID: 28098897
    2. activated ARF3 is associated with Unc93B1 and TLR9, suggesting that ARF3 conducts TLR9 trafficking by forming the TLR9-Unc93B1-ARF3 complex. PMID: 26067373
    3. ARF1+ARF3 are required for integrity of recycling endosomes but are involved in distinct transport pathways: they are required for the transferrin recycling pathway from endosomes to the plasma membrane. PMID: 23783033
    4. These results suggest that Arf3 plays a unique function at the trans-Golgi network that likely involves recruitment by a specific receptor. PMID: 20357002
    5. expression and subcellular redistribution by heregulin PMID: 12135740

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  • 亞細(xì)胞定位：
    Golgi apparatus. Cytoplasm, perinuclear region.
  • 蛋白家族：
    Small GTPase superfamily, Arf family
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 654

    OMIM: 103190

    KEGG: hsa:377

    STRING: 9606.ENSP00000256682

    UniGene: Hs.119177