ARHGAP20 Antibody

說(shuō)明書

產(chǎn)品詳情

Uniprot No.：

Q9P2F6
基因名：

ARHGAP20
別名：

ARHGAP20 antibody; KIAA1391 antibody; Rho GTPase-activating protein 20 antibody; Rho-type GTPase-activating protein 20 antibody
宿主：

Rabbit
反應(yīng)種屬：

Human,Mouse,Rat
免疫原：

Human ARHGAP20
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA,WB
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.
基因功能參考文獻(xiàn)：
1. The similar expression profiles of ARHGAP20 in 13q14 and 11q22-23 deleted CLL cases suggest a molecular connection and an intriguing mechanism of regulation PMID: 21500311
2. human KIAA1391 gene and mouse Kiaa1391 gene encode RhoGAP proteins with RA domain and two ANXL repeats PMID: 14532992
3. RA-RhoGAP transduces a signal from Rap1 to Rho and regulates the neurite outgrowth PMID: 16014623
相關(guān)疾?。?/div>
A chromosomal aberration involving ARHGAP20 may be a cause of B-cell chronic lymphocytic leukemia (B-CLL) (PubMed:15543602). Translocation t(X;11)(q21;q23) with BRWD3 does not result in fusion transcripts but disrupts both genes (PubMed:15543602).
組織特異性：

Expressed predominantly in the brain. Lower expression is found in lymph nodes.
數(shù)據(jù)庫(kù)鏈接：

HGNC: 18357

OMIM: 609568

KEGG: hsa:57569

STRING: 9606.ENSP00000260283

UniGene: Hs.6136