ARHGEF10L Antibody

說明書

產(chǎn)品詳情

Uniprot No.：

Q9HCE6
基因名：

ARHGEF10L
別名：

ARGAL_HUMAN antibody; ARHGEF10L antibody; GrinchGEF antibody; KIAA1626 antibody; Rho guanine nucleotide exchange factor 10-like protein antibody; RP11-473A10.1 antibody
宿主：

Rabbit
反應(yīng)種屬：

Human,Mouse
免疫原：

Human ARHGEF10L
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA,WB
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Acts as guanine nucleotide exchange factor (GEF) for RHOA, RHOB and RHOC.
基因功能參考文獻(xiàn)：
1. Inherited variants in ARHGEF10L and AKAP6, with potential transcriptional regulatory function and association with Epithelial ovarian cancer risk, warrant investigation in independent Epithelial ovarian cancer study populations. PMID: 29979793
2. In intact cells, GrinchGEF induced specifically Rho activation and enhanced RhoA-C-specific downstream effects. PMID: 16112081
亞細(xì)胞定位：

Cytoplasm.
組織特異性：

Detected in heart, liver, skeletal muscle, kidney and pancreas.
數(shù)據(jù)庫鏈接：

HGNC: 25540

OMIM: 612494

KEGG: hsa:55160

STRING: 9606.ENSP00000355060

UniGene: Hs.443460