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ARSE Antibody

  • 中文名稱：
    ARSE兔多克隆抗體
  • 貨號：
    CSB-PA002146LA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • IHC image of CSB-PA002146LA01HU diluted at 1:400 and staining in paraffin-embedded human liver tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • IHC image of CSB-PA002146LA01HU diluted at 1:400 and staining in paraffin-embedded human pancreatic tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) ARSE Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    ARSE
  • 別名：
    ARSL antibody; ARSE antibody; Arylsulfatase L antibody; EC 3.1.6.- antibody; Arylsulfatase E antibody; ASE antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Arylsulfatase E protein (352-494AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，ARSE Antibody (CSB-PA002146LA01HU)，的標記方式是Non-conjugated。對于ARSE Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA002146LB01HU ARSE Antibody, HRP conjugated ELISA
    FITC CSB-PA002146LC01HU ARSE Antibody, FITC conjugated
    Biotin CSB-PA002146LD01HU ARSE Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:200-1:500
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Exhibits arylsulfatase activity towards the artifical substrate 4-methylumbelliferyl sulfate. May be essential for the correct composition of cartilage and bone matrix during development. Has no activity toward steroid sulfates.
  • 基因功能參考文獻：
    1. Data indicate that the neonatal detection test sensitivity obtained was 95% with a positive predictive value of 1 in the analyses for both the arylsulfatase E (ARSE) and melanoma antigen family H1 (MAGEH1) genes. PMID: 25366798
    2. Results show that Around 40 perdcent of male patients with brachytelephalangic chondrodysplasia punctata do not have detectable ARSE mutations or known maternal etiological factors. PMID: 23470839
    3. Clinical and molecular analysis of ARSE in CDPX1 patients supports heterogeneity for CDPX1-like phenotypes and sorting these out will help to define the biological pathway and genetic contributors. [ARSE] PMID: 18348268
  • 相關疾?。?/div>
    Chondrodysplasia punctata 1, X-linked recessive (CDPX1)
  • 亞細胞定位：
    Golgi apparatus, Golgi stack.
  • 蛋白家族：
    Sulfatase family
  • 組織特異性：
    Expressed in the pancreas, liver and kidney.
  • 數(shù)據庫鏈接：

    HGNC: 719

    OMIM: 300180

    KEGG: hsa:415

    STRING: 9606.ENSP00000370526

    UniGene: Hs.386975