ASGR2 Antibody

說明書

產(chǎn)品詳情

Uniprot No.：

P07307
基因名：

ASGR2
別名：

ASGR2; CLEC4H2; Asialoglycoprotein receptor 2; ASGP-R 2; ASGPR 2; C-type lectin domain family 4 member H2; Hepatic lectin H2; HL-2
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Human ASGR2
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA,WB
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface.
基因功能參考文獻(xiàn)：
1. sH2a has the potential to be a uniquely sensitive and specific novel marker for liver fibrosis and function. PMID: 22096539
2. trafficks intracellularly and forms homo-oligomers, but does not bind asialo-orosomucoid PMID: 12089159
亞細(xì)胞定位：

Membrane; Single-pass type II membrane protein.
組織特異性：

Expressed exclusively in hepatic parenchymal cells.
數(shù)據(jù)庫鏈接：

HGNC: 743

OMIM: 108361

KEGG: hsa:433

STRING: 9606.ENSP00000347140

UniGene: Hs.654440