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AVIL Antibody

  • 中文名稱(chēng)：
    AVIL兔多克隆抗體
  • 貨號(hào)：
    CSB-PA002464GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    AVIL
  • 別名：
    Actin binding protein DOC 6 antibody; Actin binding protein DOC6 antibody; Advil antibody; Advillin antibody; AVIL antibody; AVIL_HUMAN antibody; DOC 6 antibody; DOC6 antibody; p92 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse
  • 免疫原：
    Human AVIL
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Ca(2+)-regulated actin-binding protein which plays an important role in actin bundling. May have a unique function in the morphogenesis of neuronal cells which form ganglia. Required for SREC1-mediated regulation of neurite-like outgrowth. Plays a role in regenerative sensory axon outgrowth and remodeling processes after peripheral injury in neonates. Involved in the formation of long fine actin-containing filopodia-like structures in fibroblast. Plays a role in ciliogenesis. In podocytes, controls lamellipodia formation through the regulation of EGF-induced diacylglycerol generation by PLCE1 and ARP2/3 complex assembly.
  • 基因功能參考文獻(xiàn)：
    1. NMR structure of the C-terminal headpiece subdomains of advillin. Evaluation of F-actin-binding requirements. PMID: 15096633
    2. Predicting the effect of a point mutation on a protein fold: the villin and advillin headpieces and their Pro62Ala mutants. PMID: 18022635
  • 亞細(xì)胞定位：
    Cytoplasm, cytoskeleton. Cell projection, lamellipodium. Cell junction, focal adhesion. Cell projection, neuron projection. Cell projection, axon.
  • 蛋白家族：
    Villin/gelsolin family
  • 組織特異性：
    Most highly expressed in the small intestine and colonic lining. Weaker expression also detected in the thymus, prostate, testes and uterus. Expressed in podocytes (at protein level).
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 14188

    OMIM: 613397

    KEGG: hsa:10677

    STRING: 9606.ENSP00000257861

    UniGene: Hs.584854