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BLLF1 Antibody, Biotin conjugated

Rare Species
  • 中文名稱：
    BLLF1兔多克隆抗體, Biotin偶聯(lián)
  • 貨號：
    CSB-PA360986LD01EFA
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Epstein-Barr virus BLLF1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    BLLF1
  • 別名：
    BLLF1 antibody; Envelope glycoprotein GP350 antibody; Membrane antigen antibody; MA antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Epstein-Barr virus
  • 免疫原：
    Recombinant Epstein-Barr virus Envelope glycoprotein GP350 protein (1-493AA)
  • 免疫原種屬：
    Epstein-Barr virus
  • 標(biāo)記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Initiates virion attachment to host B-lymphocyte cell, leading to virus entry. Acts by binding to host CR2 at the surface of B-lymphocytes, facilitating the binding of viral glycoprotein gp42 to HLA class II molecules. Attachment triggers virion-host membrane fusion and invasion of the host cell.
  • 基因功能參考文獻：
    1. The similar distribution of gp350/220 variants in nasopharyngeal carcinoma, EBV-associated gastric carcinoma and healthy donors suggest that gp350/220 variations are geographically restricted rather than tumor-specific polymorphisms. PMID: 22038027
    2. gp350 mainly exerts its functions after the internalization step, presumably during release of the viral capsid from the endosomal compartment, and that CD21-dependent but also CD21-independent molecular mechanisms are involved in this process. PMID: 19889766
    3. X-ray structure of the highly glycosylated gp350; defined the CR2 binding site on gp350, deglycosylated gp350 bound CR2 similarly to the glycosylated form, suggesting that glycosylation is not important for receptor binding PMID: 17072314
    4. These site-directed mutations identified a novel negatively charged complement receptor type 2-binding surface described by residues Glu-21, Asp-22, Glu-155, Asp-208, Glu-210, and Asp-296. PMID: 18786993
  • 亞細胞定位：
    Virion membrane; Single-pass membrane protein. Host membrane; Single-pass membrane protein. Note=Most abundant component of the viral envelope.
  • 蛋白家族：
    Epstein-Barr GP350 family
  • 數(shù)據(jù)庫鏈接：

    KEGG: vg:3783713