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  4. CAMK2N1 Antibody, Biotin conjugated

CAMK2N1 Antibody, Biotin conjugated

  • 中文名稱：
    CAMK2N1兔多克隆抗體, Biotin偶聯(lián)
  • 貨號：
    CSB-PA004469ND01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) CAMK2N1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    CAMK2N1
  • 別名：
    CAMK2N1Calcium/calmodulin-dependent protein kinase II inhibitor 1 antibody; CaMKII inhibitory protein alpha antibody; CaMKIIN-alpha antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Peptide sequence from Human Calcium/calmodulin-dependent protein kinase II inhibitor 1 protein (9-27AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    Potent and specific inhibitor of CaM-kinase II (CAMK2).
  • 基因功能參考文獻(xiàn)：
    1. CAMK2N1 expression is significantly downregulated in human masticatory mucosa during wound healing PMID: 28005267
    2. Hypermethylation of RUNX3/CAMK2N1 is associated with poor clinical outcome in Type II EOC, also after macroscopic complete resection. PMID: 26175272
    3. contributes to prostate cancer growth and survival through androgen receptor-dependent signaling PMID: 25296973
    4. Analyses suggest that CAMK2N1 plays a tumor suppressive role in prostate cancer cells. Reduced CAMK2N1 expression correlates to human prostate cancer progression and predicts poor clinical outcome. PMID: 25003983
    5. hCaMKIINalpha suppresses tumor growth by inducing cell cycle arrest via p27 stabilization PMID: 18305109

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  • 亞細(xì)胞定位：
    Cell junction, synapse, synaptosome. Cell junction, synapse, postsynaptic density.
  • 蛋白家族：
    CAMK2N family
  • 組織特異性：
    Widely expressed. Nor detected in skeletal muscle.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 24190

    OMIM: 614986

    KEGG: hsa:55450

    UniGene: Hs.731383