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CHAD Antibody

  • 中文名稱：
    CHAD兔多克隆抗體
  • 貨號：
    CSB-PA005310GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    Cartilage leucine rich protein antibody; Cartilage leucine-rich protein antibody; Chad antibody; CHAD_HUMAN antibody; Chondroadherin antibody; Chondroadherin proteoglycan antibody; SLRR4A antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human CHAD
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能：
    Promotes attachment of chondrocytes, fibroblasts, and osteoblasts. This binding is mediated (at least for chondrocytes and fibroblasts) by the integrin alpha(2)beta(1). May play an important role in the regulation of chondrocyte growth and proliferation.
  • 基因功能參考文獻(xiàn)：
    1. crystal structures at ~2.2A resolution of human fibromodulin and chondroadherin. PMID: 28215822
    2. number of cells adhering via their beta(1) integrin receptor to collagen type II or chondroadherin was profoundly and rapidly enhanced by the addition of the heparin-binding peptide PMID: 23172228
    3. chondroadherin interaction with cells may be central for maintaining the adult chondrocyte phenotype and cartilage homeostasis. PMID: 21127050
    4. Changes in CHAD abundance or structure could be associated with the pathologic changes occurring in the scoliotic IVD. PMID: 19525844
  • 亞細(xì)胞定位：
    Secreted, extracellular space, extracellular matrix.
  • 蛋白家族：
    Small leucine-rich proteoglycan (SLRP) family, SLRP class IV subfamily
  • 組織特異性：
    Present in chondrocytes at all ages.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 1909

    OMIM: 602178

    KEGG: hsa:1101

    STRING: 9606.ENSP00000258969

    UniGene: Hs.97220