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  4. CLGN Antibody

CLGN Antibody

  • 中文名稱：
    CLGN兔多克隆抗體
  • 貨號：
    CSB-PA005544GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    CLGN
  • 別名：
    CLGN; Calmegin
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human CLGN
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Functions during spermatogenesis as a chaperone for a range of client proteins that are important for sperm adhesion onto the egg zona pellucida and for subsequent penetration of the zona pellucida. Required for normal sperm migration from the uterus into the oviduct. Required for normal male fertility. Binds calcium ions.
  • 基因功能參考文獻：
    1. In gene-based analysis CLGN1 represented one of a cluster of genes, which interacted with sodium to influence Blood Pressure. PMID: 27271309
    2. Although their similarity in carbohydrate binding specificities is high, there seems to be some differences in the mode of substrate recognition between calmegin and calnexin. PMID: 24769397
    3. calmegin expression is regulated by histone deacetylase and CpG methyltransferase in a coordinative way PMID: 16264275
  • 亞細胞定位：
    Endoplasmic reticulum membrane; Single-pass type I membrane protein.
  • 蛋白家族：
    Calreticulin family
  • 組織特異性：
    Detected in testis (at protein level). Detected in testis.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 2060

    OMIM: 601858

    KEGG: hsa:1047

    STRING: 9606.ENSP00000326699

    UniGene: Hs.86368