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COQ5 Antibody

  • 中文名稱(chēng)：
    COQ5兔多克隆抗體
  • 貨號(hào)：
    CSB-PA005804GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    COQ5
  • 別名：
    COQ52-methoxy-6-polyprenyl-1,4-benzoquinol methylase antibody; mitochondrial antibody; EC 2.1.1.201 antibody; Ubiquinone biosynthesis methyltransferase COQ5 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human COQ5
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB,IHC
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
  • 基因功能參考文獻(xiàn)：
    1. This is the first report of primary CoQ10 deficiency caused by loss of function of COQ5, with delineation of the clinical, laboratory, histological, and molecular features, and insights regarding targeted treatment with CoQ10 supplementation. PMID: 29044765
    2. The expression of COQ5 was increased. PMID: 27155576
    3. The results that knockdown of the COQ5 gene reduced CoQ10 levels further indicated the critical role of COQ5 in the biosynthesis of CoQ10. PMID: 23354120
  • 亞細(xì)胞定位：
    Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
  • 蛋白家族：
    Class I-like SAM-binding methyltransferase superfamily, MenG/UbiE family
  • 組織特異性：
    Widely expressed, with highest levels in liver, lung, placenta and skeletal muscle.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 28722

    OMIM: 616359

    KEGG: hsa:84274

    STRING: 9606.ENSP00000288532

    UniGene: Hs.17250