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  4. COQ7 Antibody

COQ7 Antibody

  • 中文名稱：
    COQ7兔多克隆抗體
  • 貨號：
    CSB-PA859111ESR1HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Western blot
      All lanes: Ubiquinone biosynthesis protein COQ7 homolog antibody at 6μg/ml + Rat heart tissue
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 25, 21 kDa
      Observed band size: 25 kDa
    • Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA859111ESR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA859111ESR1HU at dilution of 1:100
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) COQ7 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    COQ7
  • 別名：
    COQ7 antibody; 5-demethoxyubiquinone hydroxylase antibody; mitochondrial antibody; DMQ hydroxylase antibody; EC 1.14.13.- antibody; Timing protein clk-1 homolog antibody; Ubiquinone biosynthesis monooxygenase COQ7 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human, Rat
  • 免疫原：
    Recombinant Human 5-demethoxyubiquinone hydroxylase, mitochondrial protein (37-217AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:200-1:1000
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone-independent manner.
  • 基因功能參考文獻：
    1. cCOQ7 COQ7 vCOQ7 PMID: 28409910
    2. Mitochondrial COQ9 is a lipid-binding protein that associates with COQ7 to enable coenzyme Q biosynthesis. PMID: 25339443
    3. action of clioquinol on several age-dependent neurodegenerative diseases with distinct etiologies might result from a slowing down of the aging process through action of the drug on CLK-1. PMID: 18927074
    4. The siRNA-mediated knock down leads to an increase in cytoplasmic superoxide dismutase (SOD1) mRNA levels and activity PMID: 19135146
  • 相關疾?。?/div>
    Coenzyme Q10 deficiency, primary, 8 (COQ10D8)
  • 亞細胞定位：
    Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
  • 蛋白家族：
    COQ7 family
  • 組織特異性：
    Expressed dominantly in heart and skeletal muscle.
  • 數據庫鏈接：

    HGNC: 2244

    OMIM: 601683

    KEGG: hsa:10229

    STRING: 9606.ENSP00000322316

    UniGene: Hs.157113