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CYP3A7 Antibody

  • 中文名稱：
    CYP3A7兔多克隆抗體
  • 貨號(hào)：
    CSB-PA007546
  • 規(guī)格：
    ￥1090
  • 圖片：
    • Western Blot analysis of 293T cells using CYP3A7 Polyclonal Antibody
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    CYP3A7
  • 別名：
    Aryl hydrocarbon hydroxylase antibody; CP37 antibody; CP3A7_HUMAN antibody; CYP3A7 antibody; CYPIIIA7 antibody; Cytochrome P450 3A7 antibody; Cytochrome P450; family 3; subfamily A; polypeptide 7 antibody; Cytochrome P450; subfamily IIIA; polypeptide 7 antibody; Cytochrome P450-HFLA antibody; Flavoprotein linked monooxygenase antibody; Flavoprotein-linked monooxygenase antibody; Microsomal monooxygenase antibody; P 450(HFL33) antibody; P 450111A7 antibody; P450 HFLA antibody; Xenobiotic monooxygenase antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human CYP3A7.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    WB, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:20000
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    A cytochrome P450 monooxygenase involved in the metabolism of steroid hormones and vitamins during embryogenesis. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Metabolizes 3beta-hydroxyandrost-5-en-17-one (dehydroepiandrosterone, DHEA), a precursor in the biosynthesis of androgen and estrogen steroid hormones. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1), particularly D-ring hydroxylated estrone at the C16-alpha position. Mainly hydroxylates all trans-retinoic acid (atRA) to 4-hydroxyretinoate and may play a role in atRA clearance during fetal development. Also involved in the oxidative metabolism of xenobiotics including anticonvulsants.
  • 亞細(xì)胞定位：
    Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
  • 蛋白家族：
    Cytochrome P450 family
  • 組織特異性：
    Expressed in fetal liver (at protein level).
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 2640

    OMIM: 605340

    KEGG: hsa:100861540

    STRING: 9606.ENSP00000337450

    UniGene: Hs.111944