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  3. 多克隆抗體
  4. Chc Antibody
  • 中文名稱：
    Chc兔多克隆抗體
  • 貨號(hào)：
    CSB-PA333472XA01DLU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Western Blot
      Positive WB detected in: recombinant protein
      All lanes: Chc Antibody at 1:1000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 33 kDa
      Observed band size: 33 kDa
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    Chc
  • 別名：
    Clathrin heavy chain Chc CG9012
  • 反應(yīng)種屬：
    Drosophila melanogaster (Fruit fly)
  • 免疫原：
    Recombinant Drosophila melanogaster (Fruit fly) Chc protein (1-260aa)
  • 免疫原種屬：
    Drosophila melanogaster (Fruit fly)
  • 標(biāo)記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Affinity-chromatography
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
  • 基因功能參考文獻(xiàn)：
    1. Bic-D is also required to transport Chc mRNA into the oocyte and for transport and proper localization of Chc protein to the oocyte cortex. PMID: 24718986
    2. Results report a Drosophila disabled (DAB)mutant revealing a novel role for DAB proteins in chemical synaptic transmission, and support a role for clathrin-mediated endocytosis in rapid clearance of neurotransmitter release sites. PMID: 21606364
    3. Bicaudal-D binds clathrin heavy chain to promote its transport and augments synaptic vesicle recycling. PMID: 20111007
    4. chc mRNA and protein are highly expressed from early stages of embryogenesis onwards, consistent with genetic studies predicting a maternal contribution of the gene function PMID: 19577664
    5. Chc is critical for synaptic vesicle recycling and in the absence of the protein, bulk retrieval mediates massive synaptic membrane internalization. PMID: 18762582

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  • 亞細(xì)胞定位：
    Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side. Note=Cytoplasmic face of coated pits and vesicles.
  • 蛋白家族：
    Clathrin heavy chain family
  • 數(shù)據(jù)庫(kù)鏈接：

    KEGG: dme:Dmel_CG9012

    STRING: 7227.FBpp0073966

    UniGene: Dm.3174