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  4. Cytotoxin 4 Antibody, Biotin conjugated

Cytotoxin 4 Antibody, Biotin conjugated

  • 中文名稱：
    Cytotoxin 4兔多克隆抗體, Biotin偶聯(lián)
  • 貨號(hào)：
    CSB-PA355645LD01NFG
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Naja atra N/A Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    N/A
  • 別名：
    antibody; Cytotoxin 4 antibody; CTX-4M antibody; CTX4 antibody; Cardiotoxin A4 antibody; CTX A4 antibody; Cardiotoxin analog IV antibody; CTX IV antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Naja atra
  • 免疫原：
    Recombinant Naja atra Cytotoxin 4 protein (22-81AA)
  • 免疫原種屬：
    Naja atra
  • 標(biāo)記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Basic protein that bind to cell membrane and depolarizes cardiomyocytes. This cytotoxin also shows lytic activities, but 2-fold more important than that of CTX-A2. It binds to the integrin alpha-V/beta-3 with a moderate affinity. Inhibits protein kinase C. It may interact with sulfatides in the cell membrane, which induces pore formation and cell internalization and is responsible for cytotoxicity in cardiomyocytes. It also may target the mitochondrial membrane and induces mitochondrial swelling and fragmentation.
  • 亞細(xì)胞定位：
    Secreted. Target cell membrane.
  • 蛋白家族：
    Snake three-finger toxin family, Short-chain subfamily, Type IA cytotoxin sub-subfamily
  • 組織特異性：
    Expressed by the venom gland.