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DDX24 Antibody

  • 中文名稱(chēng):
    DDX24兔多克隆抗體
  • 貨號(hào):
    CSB-PA050498
  • 規(guī)格:
    ¥2024
  • 圖片:
    • Immunohistochemistry analysis of paraffin-embedded human brain tissue using DDX24 antibody.
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱(chēng):
    Rabbit anti-Homo sapiens (Human) DDX24 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    DDX24
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Synthesized peptide derived from internal of Human DDX24.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 克隆類(lèi)型:
    Polyclonal
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:50-1:100
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    ATP-dependent RNA helicase.
  • 基因功能參考文獻(xiàn):
    1. DDX24 is a negative regulator of p53 transcriptional activity.DDX24 inhibits p300 mediated acetylation of p53. PMID: 25867071
    2. depletion of DDX24 in cells impaired pre-rRNA processing and resulted both in abrogation of MDM2 function and in consequent p53 stabilization PMID: 24980433
    3. knockdown of a DEAD-box protein named DDX24 inhibits the packaging of HIV-1 RNA and thus diminishes viral infectivity. PMID: 18289627
  • 蛋白家族:
    DEAD box helicase family, DDX24/MAK5 subfamily
  • 組織特異性:
    Ubiquitous. Most abundant in heart and brain, but with lowest levels in thymus and small intestine.
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 13266

    OMIM: 606181

    KEGG: hsa:57062

    STRING: 9606.ENSP00000328690

    UniGene: Hs.510328