DDX46 Antibody

說明書

產(chǎn)品詳情

Uniprot No.：

Q7L014
基因名：

DDX46
別名：

DDX46 antibody; KIAA0801Probable ATP-dependent RNA helicase DDX46 antibody; EC 3.6.4.13 antibody; DEAD box protein 46 antibody; PRP5 homolog antibody
宿主：

Rabbit
反應(yīng)種屬：

Human,Mouse,Rat
免疫原：

Human DDX46
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA,WB,IF
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunofluorescence (IF) Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Plays an essential role in splicing, either prior to, or during splicing A complex formation.
基因功能參考文獻(xiàn)：
1. Knockdown of DDX46 inhibited osteosarcoma cell proliferation. PMID: 27697093
2. DDX46 is critical for ESCC cells proliferation. PMID: 27176873
3. DDX46 is critical for colorectal cancer (CRC) cell proliferation and is a potential therapeutic target for CRC treatment. PMID: 25680556
4. Short-term exercise resulted in a significant increase of mRNA expression of genes encoding proteins involved in the formation of precatalytic splisosome: DDX46. PMID: 19902070
5. characterization of protein associated with the human 17S U2 snRNP and one of its stable subunits, SF3b; results indicate that Prp5 plays an important role in pre-mRNA splicing, acting during or prior to prespliceosome assembly PMID: 12234937
6. Prp5 forms a bridge between U1 and U2 Small Nuclear Ribonucleoproteins at the time of pre-spliceosome formation PMID: 14713954
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亞細(xì)胞定位：

Nucleus speckle. Nucleus, Cajal body. Membrane; Lipid-anchor. Note=Present in Cajal bodies (CBs) and nuclear speckles.
蛋白家族：

DEAD box helicase family, DDX46/PRP5 subfamily
數(shù)據(jù)庫鏈接：

HGNC: 18681

OMIM: 617848

KEGG: hsa:9879

STRING: 9606.ENSP00000346236

UniGene: Hs.406549