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  4. DEUP1 Antibody, FITC conjugated

DEUP1 Antibody, FITC conjugated

  • 中文名稱：
    DEUP1兔多克隆抗體, FITC偶聯(lián)
  • 貨號：
    CSB-PA004729LC01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) DEUP1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    DEUP1
  • 別名：
    DEUP1 antibody; CCDC67 antibody; Deuterosome assembly protein 1 antibody; Coiled-coil domain-containing protein 67 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Deuterosome assembly protein 1 protein (217-292AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Key structural component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells. Deuterosome-mediated centriole amplification occurs in terminally differentiated multiciliated cells and can generate more than 100 centrioles. Probably sufficient for the specification and formation of the deuterosome inner core. Interacts with CEP152 and recruits PLK4 to activate centriole biogenesis.
  • 基因功能參考文獻：
    1. Single nucleotide polymorphism in CCDC67 gene is associated with Acute Renal Graft Rejection. PMID: 27272414
    2. Loss of CCDC67 is associated with papillary thyroid carcinoma. PMID: 26716505
    3. suggest that CCDC67 is a putative tumor suppressor gene that is silenced in gastric cancers by promoter CpG methylation and that it may play an important role in cell signaling and migration related to tumorigenesis PMID: 22610074
  • 亞細胞定位：
    Cytoplasm.
  • 蛋白家族：
    CEP63 family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 26344

    KEGG: hsa:159989

    STRING: 9606.ENSP00000298050

    UniGene: Hs.436625