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DGKG Antibody

  • 中文名稱：
    DGKG兔多克隆抗體
  • 貨號(hào)：
    CSB-PA006836LA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Western blot
      All lanes: DGKG antibody at 4µg/ml + Mouse brain tissue
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 90, 87, 85 kDa
      Observed band size: 90 kDa
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品描述：

    To produce the polyclonal antibody that targets DGKG, rabbits were immunized with the recombinant human DGKG protein (1-255aa). Afterward, this DGKG polyclonal antibody was purified using protein G affinity chromatography, resulting in a purity level exceeding 95%. It can recognize and bind to DGKG protein present in human and mouse samples.

    This DGKG polyclonal antibody has undergone rigorous validation and is appropriate for use in ELISA and WB. As such, it can be utilized to assess DGKG protein levels and detect its presence and size in different experimental contexts.

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) DGKG Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    DGKG antibody; DAGK3Diacylglycerol kinase gamma antibody; DAG kinase gamma antibody; EC 2.7.1.107 antibody; Diglyceride kinase gamma antibody; DGK-gamma antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human, Mouse
  • 免疫原：
    Recombinant Human Diacylglycerol kinase gamma protein (1-255AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁(yè)面中的產(chǎn)品，DGKG Antibody (CSB-PA006836LA01HU)，的標(biāo)記方式是Non-conjugated。對(duì)于DGKG Antibody，我們還提供其他標(biāo)記。見(jiàn)下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號(hào) 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA006836LB01HU DGKG Antibody, HRP conjugated ELISA
    FITC CSB-PA006836LC01HU DGKG Antibody, FITC conjugated
    Biotin CSB-PA006836LD01HU DGKG Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids. Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes. Has no apparent specificity with regard to the acyl compositions of diacylglycerol. Specifically expressed in the cerebellum where it controls the level of diacylglycerol which in turn regulates the activity of protein kinase C gamma. Through protein kinase C gamma, indirectly regulates the dendritic development of Purkinje cells, cerebellar long term depression and ultimately cerebellar motor coordination.
  • 基因功能參考文獻(xiàn)：
    1. Epigenetic silencing of DGKG expression is associated with skin cancer. PMID: 28218473
    2. these results indicate that DGKG is an anionic phospholipid binding protein that preferably interacts with a small highly charged head group that is very close to the glycerol or sphingosine backbone. PMID: 24486543
    3. diacylglycerol kinase gamma regulates macrophage differentiation. PMID: 12732202
    4. the interaction of diacylglycerol kinase gamma with the Src homology 2 and C1 domains of beta2-chimaerin is induced synergistically by Phorbol ester and hydrogen peroxide PMID: 17803461
  • 亞細(xì)胞定位：
    Membrane. Cytoplasm, cytosol. Cytoplasm, cytoskeleton.
  • 蛋白家族：
    Eukaryotic diacylglycerol kinase family
  • 組織特異性：
    Predominantly expressed in retina and in a much lesser extent in the brain. Other tissues contain extremely low levels of DGK-gamma.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 2853

    OMIM: 601854

    KEGG: hsa:1608

    STRING: 9606.ENSP00000265022

    UniGene: Hs.683449