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  4. DHRS9 Antibody

DHRS9 Antibody

  • 中文名稱：
    DHRS9兔多克隆抗體
  • 貨號：
    CSB-PA006867DA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA006867DA01HU at dilution of 1:100
    • Immunofluorescent analysis of A549 cells using CSB-PA006867DA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) DHRS9 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    DHRS9
  • 別名：
    3 alpha hydroxysteroid dehydrogenase antibody; 3-@alpha-HSD antibody; 3-@alpha-hydroxysteroid dehydrogenase antibody; 3-alpha hydroxysteroid dehydrogenase antibody; 3-alpha-HSD antibody; 3alpha HSD antibody; Dehydrogenase/reductase SDR family member 9 antibody; DHRS9 antibody; DHRS9_HUMAN antibody; NADP dependent retinol dehydrogenase/reductase antibody; NADP-dependent retinol dehydrogenase/reductase antibody; RDH-E2 antibody; Rdh15 antibody; RDHE2 antibody; RDHL antibody; RDHTBE antibody; retinol dehydrogenase homolog antibody; Retinol dehydrogenase; tracheobronchiol epithelail cell-specific antibody; RETSDR8 antibody; SDR family; member 9 antibody; SDR9C4 antibody; short chain dehydrogenase/reductase family 9 antibody; short chain dehydrogenase/reductase family 9C; member 4 antibody; Short chain dehydrogenase/reductase retSDR8 antibody; Short-chain dehydrogenase/reductase retSDR8 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Dehydrogenase/reductase SDR family member 9 protein (23-319AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，DHRS9 Antibody (CSB-PA006867DA01HU)，的標(biāo)記方式是Non-conjugated。對于DHRS9 Antibody，我們還提供其他標(biāo)記。見下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA006867DB01HU DHRS9 Antibody, HRP conjugated ELISA
    FITC CSB-PA006867DC01HU DHRS9 Antibody, FITC conjugated
    Biotin CSB-PA006867DD01HU DHRS9 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    3-alpha-hydroxysteroid dehydrogenase that converts 3-alpha-tetrahydroprogesterone (allopregnanolone) to dihydroxyprogesterone and 3-alpha-androstanediol to dihydroxyprogesterone. Plays also a role in the biosynthesis of retinoic acid from retinaldehyde. Can utilize both NADH and NADPH.
  • 基因功能參考文獻(xiàn)：
    1. The study findings suggest that DHRS9 might be a useful diagnostic and prognostic marker for oral squamous cell carcinoma PMID: 30149992
    2. DHRS9 is a specific and stable marker of human regulatory macrophages. PMID: 28594751
    3. decreased expression of DHRS9 correlates with tumor progression and may serve as a potential prognostic biomarker in colorectal cancer PMID: 26254099
    4. Even at early stages of malignant transformation, a significant decrease in ADH1B, ADH3, RDHL, and RALDH1 mRNA levels was observed in 82, 79, 73, and 64% of tumor specimens, respectively PMID: 27239845
    5. Dehydrogenase/reductase SDR family member 9 is a moonlighting protein that functions as both a metabolic enzyme and as a transcriptional repressor. PMID: 16691198
    6. expression of retinol dehydrogenase L is regulated by APC and CDX2 PMID: 15190067
    7. retinoic acid-responsive genes are induced by Epstein-Barr virus lytic infection through induction of a retinol-metabolizing enzyme, DHRS9 PMID: 17244623

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  • 亞細(xì)胞定位：
    Microsome membrane. Endoplasmic reticulum membrane. Note=Associated with microsomal membranes.
  • 蛋白家族：
    Short-chain dehydrogenases/reductases (SDR) family
  • 組織特異性：
    Highly expressed in trachea and epidermis. Detected at lower levels in spinal cord, bone marrow, brain, tongue, esophagus, heart, colon, testis, placenta, lung, skeletal muscle and lymph node.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 16888

    OMIM: 612131

    KEGG: hsa:10170

    STRING: 9606.ENSP00000316670

    UniGene: Hs.179608