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  4. DHX8 Antibody

DHX8 Antibody

  • 中文名稱：
    DHX8兔多克隆抗體
  • 貨號：
    CSB-PA002114
  • 規(guī)格：
    ￥1090
  • 圖片：
    • Western Blot analysis of HepG2 cells using DDX8 Polyclonal Antibody
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    DHX8
  • 別名：
    ATP dependent RNA helicase DHX8 antibody; ATP-dependent RNA helicase dhx8 antibody; DDX 8 antibody; DDX8 antibody; DEAD/H (Asp Glu Ala Asp/His) box polypeptide 8 (RNA helicase) antibody; DEAD/H (Asp Glu Ala Asp/His) box polypeptide 8 antibody; DEAD/H box 8 antibody; DEAD/H box polypeptide 8 antibody; DEAH (Asp Glu Ala His) box polypeptide 8 antibody; DEAH box polypeptide 8 antibody; DEAH box protein 8 antibody; DHX 8 antibody; dhx8 antibody; DHX8_HUMAN antibody; HRH 1 antibody; HRH1 antibody; PRP 22 antibody; PRP22 antibody; PRP22; S. cerevisiae; homolog of antibody; PRPF 22 antibody; PRPF22 antibody; RNA helicase HRH 1 antibody; RNA helicase HRH1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human DDX8.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    WB, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:5000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Involved in pre-mRNA splicing as component of the spliceosome. Facilitates nuclear export of spliced mRNA by releasing the RNA from the spliceosome.
  • 基因功能參考文獻：
    1. cellular complexes comprising cactin, DHX8 and SRRM2 sustain precise chromosome segregation, genome stability and cell proliferation by allowing faithful splicing of specific pre-mRNAs. PMID: 28062851
    2. structural and functional analysis of C-terminal domain of the spliceosomal helicase Prp22 PMID: 23096351
    3. Preliminary X-ray diffraction analysis of the crystals of the C-terminal domain of the human DExD/H-box protein hPrp22 at 2.1 A resolution, is reported. PMID: 19724143
  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    DEAD box helicase family, DEAH subfamily, DDX8/PRP22 sub-subfamily
  • 組織特異性：
    Expressed in skin, cervix and nerve. Also expressed in the brain.
  • 數據庫鏈接：

    HGNC: 2749

    OMIM: 600396

    KEGG: hsa:1659

    STRING: 9606.ENSP00000262415

    UniGene: Hs.463105