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DKKL1 Antibody

  • 中文名稱：
    DKKL1兔多克隆抗體
  • 貨號(hào)：
    CSB-PA892450LA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA892450LA01HU at dilution of 1:100
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) DKKL1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    DKKL1
  • 別名：
    Cancer/testis antigen 34 antibody; CT34 antibody; dickkopf like 1 antibody; Dickkopf-like protein 1 antibody; DKKL1 antibody; DKKL1_HUMAN antibody; Protein soggy-1 antibody; SGY antibody; SGY-1 antibody; SGY1 antibody; soggy 1 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Dickkopf-like protein 1 protein (31-242AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁(yè)面中的產(chǎn)品，DKKL1 Antibody (CSB-PA892450LA01HU)，的標(biāo)記方式是Non-conjugated。對(duì)于DKKL1 Antibody，我們還提供其他標(biāo)記。見下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號(hào) 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA892450LB01HU DKKL1 Antibody, HRP conjugated ELISA
    FITC CSB-PA892450LC01HU DKKL1 Antibody, FITC conjugated
    Biotin CSB-PA892450LD01HU DKKL1 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Involved in fertilization by facilitating sperm penetration of the zona pellucida. May promote spermatocyte apoptosis, thereby limiting sperm production. In adults, may reduce testosterone synthesis in Leydig cells. Is not essential either for development or fertility.
  • 基因功能參考文獻(xiàn)：
    1. DKKL was overexpressed in colorectal cancer tissue compared with healthy colon. DKKL expression positively correlated with colorectal cancer progression. PMID: 27635108
    2. previously unreported alternative splicing patterns in the genes ZNF419 and DKKL1 PMID: 27826023
    3. Findings suggest that Dkk-3 plays a role in the regulation of cell interactions during retinoic acid-induced neuronal differentiation; effect on apoptosis was also observed upon expression of the related protein Dkkl-1 PMID: 24909558
    4. DKKL1/Dkkl1 may play an important role in testicular development and spermatogenesis and may be an important factor in male infertility. PMID: 22817830
  • 亞細(xì)胞定位：
    Secreted. Cytoplasmic vesicle, secretory vesicle, acrosome.
  • 組織特異性：
    More highly expressed in adult testis than in fetal testis. Exclusively expressed in the testis (at protein level). Intense expression in stages II, III and IV of spermatogenesis, whereas expression is lower in stage I.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 16528

    OMIM: 605418

    KEGG: hsa:27120

    STRING: 9606.ENSP00000221498

    UniGene: Hs.515855