DLGAP3 Antibody

說明書

產(chǎn)品詳情

Uniprot No.：

O95886
基因名：

DLGAP3
別名：

DLGAP3 antibody; DAP3Disks large-associated protein 3 antibody; DAP-3 antibody; PSD-95/SAP90-binding protein 3 antibody; SAP90/PSD-95-associated protein 3 antibody; SAPAP3 antibody
宿主：

Rabbit
反應(yīng)種屬：

Human,Mouse,Rat
免疫原：

Human DLGAP3
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

0.1M NaHCO3,0.1M Glycine, 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA,WB
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

May play a role in the molecular organization of synapses and neuronal cell signaling. Could be an adapter protein linking ion channel to the subsynaptic cytoskeleton. May induce enrichment of PSD-95/SAP90 at the plasma membrane.
基因功能參考文獻(xiàn)：
1. several rare variants of the DLGAP3 gene were found in this study which may be associated with schizophrenia. PMID: 23414653
2. This study provides suggestive evidence that DLGAP3 and its interactive effect with SLC1A1 might be involved in susceptibility to developing OC symptoms in schizophrenia patients receiving AAP treatment. PMID: 21990008
3. This study generated preliminary evidence to link SAPAP3 variants to the development of earlier onset obsessive-compulsive disorder. PMID: 21295225
4. DLGAP3 remains a promising candidate gene for Tourette Syndrome. PMID: 21184590
5. Sapap3 is a promising functional candidate gene for human grooming disorder (obsessive compulsive disorder). PMID: 19051237
6. Multiple rare SAPAP3 missense variants in trichotillomania and OCD. PMID: 19096451
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亞細(xì)胞定位：

Cell membrane; Peripheral membrane protein. Cell junction, synapse, postsynaptic density. Cell junction, synapse.
蛋白家族：

SAPAP family
數(shù)據(jù)庫鏈接：

HGNC: 30368

OMIM: 611413

KEGG: hsa:58512

STRING: 9606.ENSP00000235180

UniGene: Hs.733945