DNASE1L1 Antibody

說明書

產(chǎn)品詳情

Uniprot No.：

P49184
基因名：

DNASE1L1
別名：

Deoxyribonuclease I-like 1 antibody; Deoxyribonuclease-1-like 1 antibody; DNAS1L1 antibody; DNase I like 1 antibody; DNase I like muscle specific antibody; DNase I lysosomal like antibody; DNase I-like 1 antibody; DNase X antibody; DNASE1L1 antibody; DNASEX antibody; DNL1L antibody; DNSL1_HUMAN antibody; Muscle specific DNase I like antibody; Muscle-specific DNase I-like antibody; XIB antibody
宿主：

Rabbit
反應(yīng)種屬：

Human,Mouse,Rat
免疫原：

Human DNASE1L1
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA,WB,IHC,IF
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

基因功能參考文獻：
1. genotyping of all 21 nonsynonymous DNase 1L1 SNPs was performed in 16 populations representing 3 ethnic groups; 2 activity-abolishing and 4 activity-reducing SNPs were confirmed to be functional; may be plausible that a minor allele of 6 SNPs producing a loss-of-function or low-activity variant could serve as a risk factor for disease PMID: 24329527
2. Yeast two-hybrid screening revealed that DNase X, a glycosylphosphatidyl inositol-anchored mammalian cell-surface protein binds EtpE-C. PMID: 24098122
3. DNASEX and TKTL1 detection in patient blood is associated with poor disease-free survival rate in oral squamous cell carcinoma. PMID: 24304513
4. Several SNPs in the deoxyribonuclease I-like 1 (DNase 1L1) and DNase 1L2 were investigated. PMID: 20967767
5. Genotyping of all the non-synonymous SNPs of was performed in three ethnic groups including six different populations using the PCR-RFLP method newly developed. PMID: 20503202
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亞細胞定位：

Endoplasmic reticulum.
蛋白家族：

DNase I family
組織特異性：

Highest levels in skeletal and cardiac muscles. Detectable in all other tissues tested except brain.
數(shù)據(jù)庫鏈接：

HGNC: 2957

OMIM: 300081

KEGG: hsa:1774

STRING: 9606.ENSP00000014935

UniGene: Hs.401929