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DTX4 Antibody

  • 中文名稱：
    DTX4兔多克隆抗體
  • 貨號(hào)：
    CSB-PA764784LA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Immunofluorescent analysis of HepG2 cells using CSB-PA764784LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) DTX4 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    Deltex4 antibody; Dtx4 antibody; DTX4_HUMAN antibody; E3 ubiquitin-protein ligase DTX4 antibody; Protein deltex-4 antibody; RING finger protein 155 antibody; RNF155 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human E3 ubiquitin-protein ligase DTX4 protein (167-432AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁(yè)面中的產(chǎn)品，DTX4 Antibody (CSB-PA764784LA01HU)，的標(biāo)記方式是Non-conjugated。對(duì)于DTX4 Antibody，我們還提供其他標(biāo)記。見下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號(hào) 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA764784LB01HU DTX4 Antibody, HRP conjugated ELISA
    FITC CSB-PA764784LC01HU DTX4 Antibody, FITC conjugated
    Biotin CSB-PA764784LD01HU DTX4 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IF 1:50-1:200
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Functions as a ubiquitin ligase protein in vivo, mediating 'Lys48'-linked polyubiquitination and promoting degradation of TBK1, targeting to TBK1 requires interaction with NLRP4.
  • 基因功能參考文獻(xiàn)：
    1. Notch is ligand activated and undergoes DTX4-mediated ubiquitylation and bilateral endocytosis before ADAM10 processing PMID: 28611181
    2. Our results provide molecular insight into the mechanisms by which NLRP4-DTX4 targets TBK1 for degradation. PMID: 22388039
  • 亞細(xì)胞定位：
    Cytoplasm.
  • 蛋白家族：
    Deltex family
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 29151

    OMIM: 616110

    KEGG: hsa:23220

    STRING: 9606.ENSP00000227451

    UniGene: Hs.523696