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EEF1D Antibody

  • 中文名稱：
    EEF1D兔多克隆抗體
  • 貨號(hào)：
    CSB-PA007431GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    EEF1D
  • 別名：
    Antigen NY CO 4 antibody; Antigen NY-CO-4 antibody; EEF 1D antibody; EEF1D antibody; EF 1 delta antibody; EF 1D antibody; EF-1-delta antibody; EF1D antibody; EF1D_HUMAN antibody; Elongation factor 1 delta antibody; Elongation factor 1-delta antibody; eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) antibody; Eukaryotic translation elongation factor 1 delta antibody; FP1047 antibody; Guanine nucleotide exchange protein antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human EEF1D
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,IHC
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP, regenerating EF-1-alpha for another round of transfer of aminoacyl-tRNAs to the ribosome.; Regulates induction of heat-shock-responsive genes through association with heat shock transcription factors and direct DNA-binding at heat shock promoter elements (HSE).
  • 基因功能參考文獻(xiàn)：
    1. eukaryotic translation elongation factor 1delta knockdown in oral squamous cell carcinoma reduced cell proliferation and induced EMT (epithelial-mesenchymal transition) phenotypes PMID: 26823560
    2. Taken together, our data suggest EFF1D functions as a novel negative regulator of SIAH-1 PMID: 21633900
    3. overexpression is positively correlated with malignant transformation of 16HBE cells induced by CdC12, but is not correlated with DNA mutations PMID: 20514991
    4. These results further confirm that overexpression of TEF-1 delta is oncogenic and the antisense TEF-1 delta mRNA expression reverses its oncogenic potential. PMID: 12210501
    5. Interaction between HrHRF and EF-1delta taken with some of the recently published information concerning the TCTP (HrHRF) mentioned above suggest a possible intracellular role for TCTP/HrHRF. PMID: 15062873
    6. Increased EF-1 delta mRNA expression is associated with lymph node metastases and advanced disease stages in esophageal carcinoma PMID: 15199388
    7. Gain of 8q-mapped EF-1 delta is associated with adverse outcome in Medulloblastoma. PMID: 16968546
    8. Repression of deltaEF1 plays a key role in mediating BMP-6-induced transcriptional activation of E-cadherin in breast cancer cells. PMID: 17997862

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  • 亞細(xì)胞定位：
    [Isoform 2]: Nucleus.
  • 蛋白家族：
    EF-1-beta/EF-1-delta family
  • 組織特異性：
    Isoform 2 is specifically expressed in brain, cerebellum and testis.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 3211

    OMIM: 130592

    KEGG: hsa:1936

    STRING: 9606.ENSP00000391944

    UniGene: Hs.333388