EFS Antibody

說明書

產(chǎn)品詳情

Uniprot No.：

O43281
基因名：

EFS
別名：

EFS antibody; CASS3Embryonal Fyn-associated substrate antibody; hEFS antibody; Cas scaffolding protein family member 3 antibody
宿主：

Rabbit
反應(yīng)種屬：

Human,Mouse,Rat
免疫原：

Human EFS
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA,WB,IF
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunofluorescence (IF) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion. May serve as an activator of SRC and a downstream effector. Interacts with the SH3 domain of FYN and with CRK, SRC, and YES.
基因功能參考文獻(xiàn)：
1. EFS and CASS4 protein function in the context of the larger CAS family group. [Review] PMID: 26119091
2. we suggest that EFS should be considered as a novel tumor suppressor gene in prostate cancer. PMID: 25296736
3. Analysis of 16 Uveal melanoma showed full methylation of the EFS CpG island in 8 (50%), no methylation in 5(31%)and partial methylation in 3 (19%)tumors. Kaplan-Meier analysis revealed higher risk of metastatic progression for tumors with EFS methylation. PMID: 21871071
蛋白家族：

CAS family
組織特異性：

The protein has been detected in lung and placenta.
數(shù)據(jù)庫鏈接：

HGNC: 16898

OMIM: 609906

KEGG: hsa:10278

STRING: 9606.ENSP00000216733

UniGene: Hs.24587