搡老女人多毛老妇女中国,日韩亚洲欧美中文高清在线,人妻少妇一区二区三区,色妞色综合久久夜夜,日本熟妇xxxx

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. EIF2B1 Antibody

EIF2B1 Antibody

  • 中文名稱：
    EIF2B1兔多克隆抗體
  • 貨號(hào)：
    CSB-PA623910ESR2HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Western blot
      All lanes: EIF2B1 antibody at 5.14µg/ml
      Lane 1: K562 whole cell lysate
      Lane 2: Mouse brain tissue
      Lane 3: Jurkat whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 34, 25 kDa
      Observed band size: 34 kDa
    • Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA623910ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA623910ESR2HU at dilution of 1:100
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) EIF2B1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    EIF2B1
  • 別名：
    EI2BA_HUMAN antibody; eIF-2B GDP-GTP exchange factor subunit alpha antibody; EIF2B antibody; Eif2b1 antibody; EIF2BA antibody; Eukaryotic translation initiation factor 2B subunit 1 alpha 26kDa antibody; Eukaryotic translation initiation factor 2B subunit alpha antibody; Translation initiation factor eIF-2B subunit alpha antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human, Mouse
  • 免疫原：
    Recombinant Human Translation initiation factor eIF-2B subunit alpha protein (1-305AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.
  • 基因功能參考文獻(xiàn)：
    1. Oligodendrocytes with truncated or deletion mutants eIF2B showed less tolerable to endoplasmic reticulum stress PMID: 26112719
    2. These data emphasize the importance of eIF2Balpha in mediating the eIF2 kinase translation-inhibitory activity and may provide insight into the complex nature of vesiculovirus oncolysis. PMID: 21795329
    3. mutational analysis of the eIF2B genes of patients with an antenatal- or early-infantile-onset encephalopathy and an early demise PMID: 14566705
    4. Biochemical analyses indicate that mutations analyzed in eIF2Balpha and -epsilon reduce the steady-state level of the affected subunit, while the most severe mutant tested, eIF2Bbeta(V341D), forms complexes with reduced stability and lower eIF2B activity. PMID: 14993275
    5. analysis of novel mutations in patients with eIF2B-related disorders PMID: 15776425
    6. Study reports 9 novel mutations in EIF2B genes in 8 patients, increasing number of known mutations to more than 120. Using homology modeling, analyzed the impact of novel mutations on the 5 subunits of eIF2B protein (alpha, beta, gamma, delta, epsilon) PMID: 18263758
    7. The authors suspected VWM and sequenced the genes EIF2B1-5, which revealed one heterozygous mutation in EIF2B4. PMID: 18330844
    8. Crystal structure of the alpha subunit of human translation initiation factor 2B. PMID: 19631657

    顯示更多

    收起更多

  • 相關(guān)疾病：
    Leukodystrophy with vanishing white matter (VWM)
  • 蛋白家族：
    EIF-2B alpha/beta/delta subunits family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 3257

    OMIM: 603896

    KEGG: hsa:1967

    STRING: 9606.ENSP00000416250

    UniGene: Hs.741273