EXD2 Antibody
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中文名稱:EXD2兔多克隆抗體
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貨號:CSB-PA873662LA01HU
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規(guī)格:¥440
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圖片:
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Western Blot
Positive WB detected in: Mouse brain tissue, Mouse stomach tissue
All lanes: EXD2 antibody at 2.8μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 71, 57 kDa
Observed band size: 71 kDa -
Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA873662LA01HU at dilution of 1:100
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Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA873662LA01HU at dilution of 1:100
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其他:
產(chǎn)品詳情
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產(chǎn)品名稱:Rabbit anti-Homo sapiens (Human) EXD2 Polyclonal antibody
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Uniprot No.:
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基因名:EXD2
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別名:4930539P14Rik antibody; C14orf114 antibody; C85658 antibody; DKFZp781A0133 antibody; DKFZp781L15100 antibody; Exd2 antibody; EXD2_HUMAN antibody; EXDL2 antibody; Exonuclease 3''-5'' domain-containing protein 2 antibody; Exonuclease 3''-5'' domain-like-containing protein 2 antibody; exonuclease 3'-5' domain-like 2 antibody; FLJ10738 antibody; RGD1311087 antibody
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宿主:Rabbit
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反應種屬:Human, Mouse
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免疫原:Recombinant Human Exonuclease 3\'-5\' domain-containing protein 2 protein (137-245AA)
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免疫原種屬:Homo sapiens (Human)
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標記方式:Non-conjugated
本頁面中的產(chǎn)品,EXD2 Antibody (CSB-PA873662LA01HU),的標記方式是Non-conjugated。對于EXD2 Antibody,我們還提供其他標記。見下表:
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克隆類型:Polyclonal
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抗體亞型:IgG
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純化方式:>95%, Protein G purified
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濃度:It differs from different batches. Please contact us to confirm it.
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保存緩沖液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產(chǎn)品提供形式:Liquid
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應用范圍:ELISA, WB, IHC
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推薦稀釋比:
Application Recommended Dilution WB 1:2000-1:10000 IHC 1:20-1:200 -
Protocols:
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儲存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途:For Research Use Only. Not for use in diagnostic or therapeutic procedures.
相關產(chǎn)品
靶點詳情
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功能:Exonuclease that has both 3'-5' exoribonuclease and exodeoxyribonuclease activities, depending on the divalent metal cation used as cofactor. In presence of Mg(2+), only shows 3'-5' exoribonuclease activity, while it shows both exoribonuclease and exodeoxyribonuclease activities in presence of Mn(2+). Acts as an exoribonuclease in mitochondrion, possibly by regulating ATP production and mitochondrial translation. Also involved in the response to DNA damage. Acts as 3'-5' exodeoxyribonuclease for double-strand breaks resection and efficient homologous recombination. Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3'-5' exonuclease activity, which efficiently processes double-stranded DNA substrates containing nicks. Also involved in response to replicative stress: recruited to stalled forks and is required to stabilize and restart stalled replication forks by restraining excessive fork regression, thereby suppressing their degradation.
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基因功能參考文獻:
- establish that EXD2 stimulates both short- and long-range DSB resection PMID: 26807646
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亞細胞定位:Mitochondrion outer membrane; Single-pass membrane protein. Mitochondrion matrix. Nucleus. Chromosome.
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蛋白家族:EXD2 family
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數(shù)據(jù)庫鏈接:
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