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EXOC3 Antibody

  • 中文名稱：
    EXOC3兔多克隆抗體
  • 貨號(hào)：
    CSB-PA527663LA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Western Blot
      Positive WB detected in: Hela whole cell lysate, MCF-7 whole cell lysate, A549 whole cell lysate, HL60 whole cell lysate, PC-3 whole cell lysate, U87 whole cell lysate
      All lanes: EXOC3 antibody at 1:2000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 87, 74, 86 kDa
      Observed band size: 87 kDa
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) EXOC3 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    EXOC3
  • 別名：
    EXOC 3 antibody; Exoc3 antibody; EXOC3_HUMAN antibody; Exocyst complex component 3 antibody; Exocyst complex component Sec 6 antibody; Exocyst complex component Sec6 antibody; rSec 6 antibody; Sec 6 antibody; Sec 6 homolog antibody; Sec 6p antibody; Sec6 antibody; SEC6 L1 antibody; SEC6 like 1 antibody; Sec6 protein antibody; SEC6L1 antibody; Sec6p antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Exocyst complex component 3 protein (410-756AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁(yè)面中的產(chǎn)品，EXOC3 Antibody (CSB-PA527663LA01HU)，的標(biāo)記方式是Non-conjugated。對(duì)于EXOC3 Antibody，我們還提供其他標(biāo)記。見下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號(hào) 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA527663LB01HU EXOC3 Antibody, HRP conjugated ELISA
    FITC CSB-PA527663LC01HU EXOC3 Antibody, FITC conjugated
    Biotin CSB-PA527663LD01HU EXOC3 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Antigen Affinity purified & Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
  • 基因功能參考文獻(xiàn)：
    1. Sec6 regulate Bcl-2 and Mcl-1 expressions but not Bcl-xl in malignant peripheral nerve sheath tumor cells. PMID: 26892009
    2. Sec6 regulates NF-kappaB transcriptional activity via the control of the phosphorylation of IkappaBalpha, p90RSK1, and ERK PMID: 26247921
    3. The study explores the role of the exocyst complex component Sec6/8 in genomic stability. PMID: 26283729
    4. Sec6 regulates cytoplasmic translocation of p27 through p27 phosphorylation at Thr157, thereby promoting p27 degradation in the cytoplasm via interaction with Jab1 and Siah1 and suppressing cell cycle progression. PMID: 24949832
    5. Data demonstrate that the expression of alpha-E-catenin is increased by Sec6 siRNAs, and E-cadherin and beta-catenin localize mainly at the cell-cell contact region in HSC3 cells, which were transfected with Sec6 siRNA. PMID: 22381337

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  • 亞細(xì)胞定位：
    Cytoplasm. Cytoplasm, perinuclear region. Cell projection, growth cone. Midbody. Golgi apparatus. Cell projection, neuron projection.
  • 蛋白家族：
    SEC6 family
  • 組織特異性：
    Expressed in epididymis (at protein level).
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 30378

    OMIM: 608186

    KEGG: hsa:11336

    STRING: 9606.ENSP00000323377

    UniGene: Hs.481464