EXOC5 Antibody

說明書

產(chǎn)品詳情

Uniprot No.：

O00471
基因名：

EXOC5
別名：

EXOC5 antibody; SEC10 antibody; SEC10L1Exocyst complex component 5 antibody; Exocyst complex component Sec10 antibody; hSec10 antibody
宿主：

Rabbit
反應(yīng)種屬：

Human,Mouse,Rat
免疫原：

Human EXOC5
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA,WB,IF
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunofluorescence (IF) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
基因功能參考文獻：
1. These data confirm that the exocyst is preferentially involved in basolateral protein translation and translocation, and may well act through the phosphorylation of Sec61beta. PMID: 23037926
2. Suggest that the exocyst sec10, acting through EGFR, endocytosis, and the MAPK pathway is a candidate therapeutic target for acute kidney injury. PMID: 25298525
3. Exocyst Sec10 overexpression reduces damage to tubular epithelial barriers caused by hydrogen peroxide and speeds the recovery of normal epithelial barrier function after such an injury. PMID: 20053792
4. Data show that GTP-bound ARF6 interacts with Sec10, a subunit of the exocyst complex involved in docking of vesicles with the plasma membrane. PMID: 14662749
5. The exocyst protein Sec10 regulates primary ciliogenesis. PMID: 19297529
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亞細胞定位：

Cytoplasm. Midbody.
蛋白家族：

SEC10 family
組織特異性：

Ubiquitous.
數(shù)據(jù)庫鏈接：

HGNC: 10696

OMIM: 604469

KEGG: hsa:10640

STRING: 9606.ENSP00000389934

UniGene: Hs.743987